Melanoma acrolentiginous Bilder

Melanoma, malignant, acrolentiginous: a slow-growing, previously asymptomatic hyperpigmentation that has existed for many years.

Melanoma, malignant, acrolentiginous: reflected light microscopy ; streaky, structureless pigmentation.

Melanoma malignes acrolentiginous: Irregularly bordered and stained completely symptom-free plaque, existing for years. I increased surface growth and development of an "unpleasant feeling" in this 42-year-old patient during the last months.

Melanoma, malignant, acrolentiginous. central amelanotic tumor with dark brown, irregular pigmentary border.

Acrolentiginous malignant melanoma: A brown, slowly increasing spot that has existed for years. It is said that this broad-based, ulcerated, repeatedly bleeding node has been formed for a few months. Arrows mark the non-node acrolentiginous part of the tumor. A weak pigmentation zone is encircled, which histologically also turned out to be melanoma infiltration.

Amelanotic acrolentiginous malignant melanoma: A "reddish spot" that has existed for years. It is said that this broad-based red node has been formed for a few months and has bled several times.

melanoma, malignant, acrolentiginous. irregularly limited, brown-black to black spot localized at the right planta pedum. according to the medical history the asymptomatic skin change has existed for several years. partly regression zones and nodular parts exist.

Melanoma, malignant, acrolentiginous: a slow-growing, previously asymptomatic, multicentric hyperpigmentation that has been present for many years; for about 1 year, increasing nodule formation with a tendency to bleed.

Melanoma malignes acrolentiginous: detailed view.

Melanoma malignes acrolentiginous: Incident light microscopy, completely irregular pigment distribution with spatter-like pigment conclusions, next to whitish areas.

Melanoma, malignant, acrolentiginous. bizarrely configured, symptomless patch of the ball of the thumb, which has been continuously enlarged for several years. following surgery of the metacarpo-phalangeal joint. the incision line was led through the melanoma, see scar in the centre.

Melanoma, malignant, acrolentiginous. detail enlargement of the right thumb: extensive, irregularly bordered, asymmetrical, brownish-black macula in the region of the distal phalanx of the thumb. scabby overlay in Z.n. Op of the distal phalanx of the thumb, incision line was led through the melanoma, see whitish scar above the melanoma.

Melanoma, malignant, acrolentiginous. 6 years of persistent, size progressive, approx. 1.8 x 1.6 cm large, darkly pigmented, flat plaque on the palmar side of the distal phalanx of the index finger in a 73-year-old man. Focal central ulceration with scabbed overlay. The borderline is blurred, an irregular and blurred demarcation to the surrounding skin tissue is visible.

Melanoma malignes acrolentiginous: Brown "spot" on the left small toe that has existed for many years; for several months now it has been growing in thickness, weeping and bleeding.

Melanoma malignes acrolentiginous: Brown "spot" on the left small toe that has existed for many years; for several months now it has been growing in thickness, weeping and bleeding.

melanoma malignes acrolentiginous. dark discoloration of the right small toe existing for years. growth of thickness for 1/2 year, discoloration increasingly decreasing. now: largely amelanotic, centrally ulcerated and macerated nodule at the 5th toe. remark: treated as mycosis for several months.

Melanoma, malignant, acrolentiginous. 2 x 3 cm diameter, red, flat, slightly putrid ulceration on the right big toe of a 73-year-old woman. At the lateral border of the ulcer there are shadowy pigment remains (circled and marked with arrows) in intact skin. In addition, palpation of the peripheral venous leg stations on the right inguinal side shows several enlarged venous leg ulcers (DD: reactive enlargement?).

Melanoma, malignant, acrolentiginous. Here: amelanotic malignant melanoma: Chronic inpatient tumor in an 80-year-old patient, existing since 2 years, localized at a pressure-exposed site, flat, sharply defined, slightly painful, similar to an ulcer, slightly raised, flat, ulcerated. The diagnosis as primary tumor was made by finding a metastasis. Note: The diagnosis of malignant melanoma in the presented case can only be made histologically. Clinically, at best, a suspected malignant tumor can be made, which must be clarified histologically.

melanoma malignes amelanotic: since earliest childhood a pigment mark has been known at this site. continuous growth for several years. for half a year extensive ulceration of the node. constant bleeding and oozing. the diagnosis cannot be made on the basis of the clinical picture.

Melanonychia striata longitudinalis: DD- subungual malignant melanoma; look for the discoloration of the cuticle (so-called Hutchinson's sign), as an indication of involvement of the nail root

DD: acrolentiginous malignant melanoma: here: Melanonychia longitudinalis:stripy (melanotic) nail pigmentation caused by a (still benign) pigment nevus localized in the (not visible) nail matrix. The anterior cut edge of the nail plate is pigment-bearing (marked with an arrow). An initial malignant melanomacan be excluded histologically with certainty.

Mlelanom malignes acrolentiginous: Subungual malignant melanoma. Characteristic is the stripy growth through the entire length of the nail. The arrow marks the so-called Hutchinson sign.

Melanoma malignant acrolentiginous: Incident light microscopy of the nail fold with tumorous infiltration.

Melanoma, malignant, acrolentiginous.

melanoma, malignant, acrolentiginous. broad, brown, continuous discoloration of the nail plate. fresh splatter-like bleeding. positive hutchinson sign (pigmentation of the cuticle and the adjacent paronychium). fresh, red bleeding (see reflected light microscopy).

melanoma, malignant, acrolentiginous. incident light microscopy. streaky, brown (melanotic) hyperpigmentation of the nail plate. complicating superimposition: fresh, red splatter-like bleeding after still recallable trauma).

Melanoma, malignant, acrolentiginous. 13 x 10 mm large, extensive, black pigmented tumor of the subungual space and distension of the nail bed of the left big toe in a 61-year-old female patient. Advanced stage with nail destruction.

Melanoma, malignant, acrolentiginous, subungual and paraungual, black pigmented tumor in the fingernail area, advanced stage with destruction of the nail.

melanoma, malignant, acrolentiginous. solitary, chronically inpatient, since years existing, slightly size progressive, indolent, recently bleeding in banal traumas, blue-black nodule, which lifts the nail matrix and has almost completely displaced it laterally. the nail itself shows a stripy, brown-black discoloration. the perionychium is brownish pigmented.

Melanoma, malignant, acrolentiginous: Complete destruction of the nail organ by tumor growth.

Melanoma, malignant, acrolentiginous: Complete destruction of the nail organ by tumor growth.

melanoma, malignant, acrolentiginous. reddish, partly skin-coloured, slowly growing, coarse plaque, which has predominantly displaced the nail bed. there are also bizarre, black-brown hyperpigmentations. the nail plate is no longer existent except for a rest.

Melanoma, malignant, acrolentiginous. solitary, chronically stationary, slowly increasing, localized at the right big toe, measuring about 0.5 cm, punched out, touch-sensitive, red ulcer covered with a dark pigmented tumor (arrow). histology: tumor thickness 2.7 mm, Clark level IV, pT3b N0 M0, stage IIB.

Amelanotic, acrolentiginous malignant melanoma : Extensive crumbly destruction of the nail plate of the big toe, arrows mark the pigment-less tumor nodes.

DD. acrolentiginous malignant melanoma: in this case nail hematoma . 6 weeks old (trauma recall), sharp blue-black discoloration of the big toe nail (marked by arrows and line) with discoloration of the epinychium (circle). arrow (right) indicates a streaky (still red) apparently fresh bleeding.

DD: Melanoma malignant acrolentiginous melanoma; here: complicating onychomycosiswith bleeding after banal trauma.

DD: Melanoma malignes acrolentiginous: here: complicating onychomycosis with bleeding due to mold infestation; the inlet points proximally, a normally colored nail area; no Hutchinson phenomenon.

Melanoma, malignant, acrolentiginous, intraepidermal and subepidermal infiltration of melanoma cells.

melanoma, malignant, acrolentiginous. irregular acanthotic epithelium with localized orthohyerkeratosis. the left part of the dermis is replaced by a largely (amelanotic) solid new formation. superficially a spindle-shaped cell type is impressive. in the marginal area there are few, clumpy melanin accumulations. the right epithelial third shows numerous atypical melanocytes in the str. basale. focal pigment incontinence is also found here.