Synonym(s)
DefinitionThis section has been translated automatically.
Benign and (rarely) malignant neoplasms, which originate from the appendages (adnexae) of the skin. The group of adnexal tumors comprises about 100 different entities.
Adnexal tumors are histologically extremely diverse, so that over the years a confusing nomenclature has developed, which is based more on outdated historical than on contemporary histogenetic facts.
Recent immunohistological findings have led to a better understanding of the histogenesis of cutaneous adnexal tumors.
Cutaneous neoplasms with ductal differentiation are divided into eccrine and apocrine, although this histological classification is not always clear.
ClassificationThis section has been translated automatically.
The diagnosis is based exclusively on histomorphological criteria. The classification is based on the visibly predominant direction of differentiation in:
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Clinical featuresThis section has been translated automatically.
Mostly uncharacteristic clinical morphology, so that the diagnosis can generally only be made histologically.
TablesThis section has been translated automatically.
Adnexal tumors of the skin
Sweat gland tumors |
Hair follicle tumors |
Sebaceous gland tumors |
Tumors of the nail organ |
|
I. Benign
II. Hamartoma III. malignant |
I. Hyperplasia II. adenoma III. epithelioma trichigenic trichoblastoma epithelioma calcificans (pilomatrixoma) desmoplastic trichoepithelioma IV. Mesodermal V. Tumors with doubtful prognosis Proliferating tricholemmal tumor Proliferating tricholemmal cyst VI. Malignant |
I. Benign Sebaceous gland hyperplasia nevus sebaceus Adenoma sebaporum (sebaceous gland adenoma II. malignant
|
I. Benign Granuloma teleangiectaticum Mucoid dorsal cyst (= pseudocyst) II. malignant |
LiteratureThis section has been translated automatically.
- Abbate M et al (2003) Clinical course, risk factors, and treatment of microcystic adnexal carcinoma: a short series report. Dermatol Surgery 29: 1035-1038
- Kaddu S et al (2002) Warty dyskeratoma--"follicular dyskeratoma": analysis of clinicopathologic features of a distinctive follicular adnexal neoplasm. J Am Acad Dermatol 47: 423-428
- McCalmont TH (1996) A call for logic in the classification of adnexal neoplasms. At J dermatopathy 18: 103-109
- Mehregan DR et al (2003) Large cell acanthoma. Int J Dermatol 42: 36-39
- Montagna W (1984) Embryology and anatomy of the cutaneous adnexa. J Cutan Pathol 11: 350-351
- Petter G, Haustein UF (2001) Rare and newly described histological variants of cutaneous squamous epithelial carcinoma. Classification by histopathology, cytomorphology and malignant potential. dermatologist 52: 288-297
- Rudolph P (2002) Benign adnexal skin tumors. Pathologist 23: 71-78
- Rütten A (2002) Eccrine sweat gland carcinoma of the skin. Pathologist 23: 79-88
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Outgoing links (7)
Adnexal tumors with apocrine differentiation; Adnexal tumors with differentiation of sebaceous glands; Adnexal tumors with eccrine differentiation; Adnexal tumors with hair follicle differentiation; Apocrine sweat gland carcinoma; Multiple Trichoepithelioma ; Nevus sebaceus;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer