Melanoma, malignant, nodular. 26-year-old woman was diagnosed with an incidental finding on the back of a solitary, coarse, asymmetrical, pearl-like bordered plaque, measuring 8 x 8 mm and increasing for more than one year. The plaque was pigmented brown-black especially at the edges with a whitish-grey centre and central scaly ruffs. Strong grey-blue streaks and massive pigment network break-offs were visible peripherally under reflected light microscopy.
Primary cutaneous anaplastic large cell (CD 30+) lymphoma. Painless, slowly progressive skin ulcer (62-year-old, otherwise healthy woman) which has been present for several months and treated as "pyoderma". Conspicuously raised wall of the ulcer and distinct induration of the reddened edges.
Keratosis seborhoeic: A slow-growing, broad-based, brown-black nodule that has been present for years; a lateral view shows the knot's sloppy growth pattern particularly well.
Central-peripheral neurofibromatosis (palmo-plantar neurofibromatosis or type III neurofibromatosis) Chronic inpatient palmo-plantar neurofibromatosis, progressive in childhood; now no longer progressive, soft, skin-colored, painless palmo-plantar nodules and plaques.
Melanoma, malignant, acrolentiginous.Here: amelanotic malignant melanoma: Chronic inpatient tumor in an 80-year-old patient, existing since 2 years, localized at a pressure-exposed site, flat, sharply defined, slightly painful, similar to an ulcer, slightly raised, flat, ulcerated. The diagnosis as primary tumor was made by finding a metastasis. Note: The diagnosis of malignant melanoma in the presented case can only be made histologically. Clinically, at best, a suspected malignant tumor can be made, which must be clarified histologically.
Plantar fibromatosis: Chronic stationary, subcutaneously located, skin-coloured to brown, approx. 5 x 4 cm large, coarse knot of a 60-year-old man, localised at the Arcus plantaris. 10 years of pressure pain and difficulties in rolling.
Hemangioma of the infant. 6-month-old girl (premature birth): Swelling of the left lower lid of a 6-month-old girl (premature birth) existing since the 2nd month of life, progressive in size, flat, blue, soft, not painful, encompassing the whole lower lid.
lymphoma, cutaneous T-cell lymphoma, large-cell, CD30-positive. detailed view: multiple, chronically dynamic, increasing, non-displaceable, confluent, hemispherical nodules covering a total area of 6 x 6 cm with hard, central, red part and deep, crater-shaped ulceration in a 64-year-old patient. the ulceration is covered with thick, yellowish coatings. the surrounding area of the ulceration is raised, livid-red and partly erosive weeping.
Dermatofibrosarcoma protuberans. solitary, chronically dynamic, continuously growing for 4-5 years, poorly delimitable to the side and depth, woody solid, smooth, bumpy, red node. the lateral depth extension clearly exceeds the protuberant part (iceberg phenomenon).
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