Synonym(s)
Adenoma sebaceum senile; circumscribed senile sebaceous hyperplasia; sebaceous hyperplasia; sebaceous hyperplasia circumscribed senile; senile sebaceous nevus
DefinitionThis section has been translated automatically.
Most frequent benign adnexal tumor with differentiation of sebaceous glands.
EtiopathogenesisThis section has been translated automatically.
Immunosuppression (e.g. after taking Ciclosporin) is beneficial.
You might also be interested in
ManifestationThis section has been translated automatically.
Occurs after the age of 35, especially in seborrhoics. Men are more frequently affected than women.
LocalizationThis section has been translated automatically.
Face, forehead, sides of the cheeks.
Clinical featuresThis section has been translated automatically.
Solitary, but mostly multiple, then disseminated, 0.2-0.5 cm in size, skin-coloured, yellowish-reddish or yellow, centrally always navelled(Cave! clinically important sign; DD basal cell carcinoma!), flat or calotte-shaped, smooth papules, which show a lobular structure and a shiny surface when viewed and illuminated laterally (and under reflected light microscopy).
Less frequently, 0.5-1.0 cm large, solitary papules or nodes with a mostly bumpy surface structure are found.
Mostly clear, accompanying seborrhoea oleosa with prominent skin pores.
HistologyThis section has been translated automatically.
Symmetrical tumour protruding the mostly unchanged epidermis, in which mature, hyperplastic sebaceous gland lobules are grouped around a central, dilated infundibulum filled with horny and sebaceous masses. Pityrosporon oval or bacterial clusters are often found in the retinal masses.
Differential diagnosisThis section has been translated automatically.
- Clinic: Basal cell carcinoma, Molluscum contagiosum
- Histology: Sebaceous adenoma.
TherapyThis section has been translated automatically.
In case of cosmetically disturbing lesions, treatment with laser (Erbium-Yag-Laser orCO2-Laser) or excision.
Note(s)This section has been translated automatically.
Confluent sebaceous gland adenomas, which cover almost the entire neck and clavicle region, are to be considered as malformation. The nosological value of the diffuse presenile sebaceous gland hyperplasia remains to be seen.
LiteratureThis section has been translated automatically.
- Finan MC, Apgar JT (1991) Juxta-clavicular beaded lines: a subepidermal proliferation of sebaceous gland elements. J Cutan catholic 18: 464-468
- Kaufmann R (1987) Diffuse (presenile) sebaceous gland hyperplasia, a new entity? dermatologist 38: 31-35
- Zouboulis C et al (2003) Ciclosporin A - induced sebaceous glands hyperplasia. Br J Dermatol 149: 198-200
Recommended articles
Incoming links (6)
Adenoma sebaceum senile; Basal cell carcinoma nodular; Sebaceous gland hyperplasia circumscripts, senile; Sebaceous gland hyperplasia diffuse presile; Sebaceous nevus, senile; Senile sebaceous nevus;Outgoing links (6)
Adnexal tumors with differentiation of sebaceous glands; Basal cell carcinoma (overview); Contagious mollusc; Sebaceous adenoma; Sebaceous gland hyperplasia diffuse presile; Seborrhoea;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer
