lupus erythematodes chronicus discoides: 25-year-old otherwise healthy patient. variable now discrete skin lesions; for 12 months. only low photosensitivity. multiple, touch-sensitive, red, plaques. histology and DIF are typical for erythematodes, ANA and ENA negative.
lupus erythematodes chronicus discoides: 35-year-old otherwise healthy patient. skin lesions since 12 months, gradually increasing, no photosensitivity. multiple, chronically stationary, touch-sensitive, red, plaques with central adherent scaling. histology and DIF are typical for erythematodes. ANA and ENA were negative.
lupus erythematodes chronicus discoides: 13-year-old otherwise healthy patient. skin lesions since 6 months, gradually increasing, no photosensitivity. several, centrofacially localized, chronically stationary, touch-sensitive (slight pain when stroking with a wooden spatula), red, slightly scaly plaques. histology and DIF are typical for erythematodes. ANA and ENA negative.
lupus erythematodes chronicus discoides: already longstanding, blurred, red, butterfly-shaped red plaques. delicate scarring beginning at the bridge of the nose. no systemic autoimmune phenomena.
lupus erythematodes chronicus discoides: 18-year-old otherwise healthy patient. skin lesions since 12 months, gradually increasing, no photosensitivity. disseminated, chronic, touch-sensitive, red , differently sized plaques with rather discrete scaling. histology and DIF are typical for erythematodes. no positive ANA and ENA.
Lupus erythematodes chronicus discoides: dry-scaling, red, hyperesthetic, plaques with adherent scaling that have existed on both halves of the face for 5 years; no evidence of systemic LE. DIF with typical pattern.
Lupus erythematodes chronicus discoides: succulent, hyperesthetic plaque with adherent scaling, 2.7x3.2 cm in size, existing for 4 months, no evidence of systemic LE. DIF with typical pattern.
Lupus erythematodes chronicus discoides : Solitary blurred plaque with atropical surface, adherent scaling, bizarrely configured scarring (bright areas); distinct painfulness in case of punctiform exposure (e.g. brushing over with fingernail); unpleasant burning sensation when exposed to UV light.
Lupus erythematodes chronicus discoides: large, sharply defined plaque with a central, clearly sunken (atrophy of the subcutaneous fatty tissue), poikilodermatic scar; the peripheral zones continue to show inflammatory activity.
Chronic (scarring) blepharitis in lupus erythematosus chronicus discoides: chronically active, red, hyperesthetic plaques with scarring and destruction of the eyelashes; focal scarring and sunken edge of the eyelid
Chronic (scarring) blepharitis in lupus erythematosus chronicus discoides: chronically active, red, hyperesthetic plaques with scarring (circle) and destruction of the eyelashes; focal scarring and sunken edge of the eyelid
Lupus erythematodes chronicus discoides: blurred, red and brown, partly slightly scaly, partly verrucous superimposed, hypersensitive plaques.
Lupus erythematosus chronicus discoides: deeply scarring discoid lupus erythematosus leading to follicle loss with complete destruction of the pigment within the lesional skin.
Lupus erythematodes chronicus discoides: blurred, red and brown, partly scaly and crusty, hypersensitive plaque, beginning scarring recognizable by the white indurated area on the left side with comedones.
Lupus erythematodes chronicus discoides: bizarrely limited white (follicular) scar with injected red scaly plaques with atrophic surface, adherent scaling; beginning mutilation of the auricular cartilage as a sign of deep-reaching inflammation.
Lupus erythematodes chronicus discoides:cutaneous chronic lupus erythematosus. years of course with circumscribed red scarring plaques (circle - with whitish atrophic area without follicular structure): arrow: dermal melanocytic nevus.
Lupus erythematosus chronicus discoides: a chronic cutaneous lupus erythematosus that has existed for several decades, with intermittent progressive, scarring (see whitish skin areas without any follicle markings).
Lupus erythematodes chronicus discoides: Condition after 2 years of continuous therapy with Resochin.
Lupus erythematodes chronicus discoides. 5 years of persistent recurrent skin changes in a 25-year-old girl, despite disease-adapted therapy measures. Large flat, soft-red plaque (with still preserved follicles). Conspicuous (re-)pigmentation within a few weeks in the lesional skin (which was hypopigmented before).
Lupus erythematodes chronicus discoides. 15 years of persistent and, despite disease-adapted therapy measures, constantly progressive skin changes in a 64-year-old patient. Large scar plate with marginal and intralesional erythema as well as isolated flat ulcers (currently covered with crust).
Lupus erythematodes chronicus discoides: CDLE leading to distinct mutilations. atrophy of skin and nasal cartilage. in the left cheek area extensive, in places deeply sunken (atrophy of the subcutaneous fatty tissue) scar with marginal (arrows) inflammatory activity
Chronic cheilitis in lupus erythematosus chronicus discoides: chronically active, red, hyperesthetic plaques with adherent scaly deposits on the lip red of the upper and lower lip; focal areas affected are lip red and lip skin.
Chronic cheilitis in lupus erythematosus chronicus discoides. Chronically active, red, hyperesthetic plaques with adherent scaly deposits on the red of the upper and lower lip.
Chronic cheilitis in lupus erythematosus chronicus discoides. Chronically active, red, hyperesthetic plaques with adherent scaly deposits on the lip red of the upper and lower lip.
Chronic cheilitis in lupus erythematosus chronicus discoides: chronically active, red, hyperesthetic plaques with adherent scaly deposits on the lip red of the upper and lower lip; focal areas affected are lip red and lip skin.
Lupus erythematodes chronicus discoides. overview: Disseminated, scarring, leading to the loss of hair follicles (clinically scarring alopecia), high parietal in a 52-year-old. surrounded by still active foci of CDLE. in the square a scarring area with in places still preserved, in places already destroyed (arrow mark) follicular structure.
Lupus erythematodes chronicus discoides: CDLE leading to significant scarring. atrophy of the skin, easily recognizable by the hair loss. in the cheek area extensive, in places deeply sunken (atrophy of the subcutaneous fatty tissue) scar with low inflammatory activity.
Lupus erythematosus chronicus discoides: chronic cutaneous lupus erythematosus that has been present for several years, progressive, disseminated, scarring, chronic cutaneous lupus erythematosus, no evidence of systemic involvement (no ANA, no DNA antibodies).
Lupus erythematosus chronicus discoides: a relapsing, progressive, disseminated, scarring, chronic cutaneous lupus erythematosus that has been present for several years. No evidence of systemic involvement (no ANA, no DNA antibodies). Here is a detailed picture.
Lupus erythematodes chronicus discoides. general view: For several years persistent, multiple, scarring, alopecic areas highlyoccipital, highly parietal and at the capillitium in a 57-year-old patient. Clear, extensive reddening of the skin of the head and face.
Lupus erythematodes chronicus discoides: older, unusual localized focus on the back of the finger.
Lupus erythematodes chronicus discoides: older, only slightly active "discoid" lupus foci that heal under atrophy of skin and subcutis (focal destruction of hair follicles) Note the reddish-livid hue of the alopecic foci.
Lupus erythematodes chronicus discoides: older, not (no longer) active, "discoid" lupus focus, healed under atrophy of skin and subcutis (complete destruction of the hair follicles, surface parchment-like smooth - see inlet).
lupus erythematodes chronicus discoides. alopecia existing for 4 years. multiple, smaller and larger alopecic foci, with centrifugal expansion. in the center larger hairless, scarred area (no evidence of follicular structures). the patient complains of a temporary hyperesthesia of the affected areas. encircles a still active zone of CDLE.
Lupus erythematodes chronicus discoides. partly spotty, partly diffuse (especially subepithelial), perivascular and also periadnexual (around eccrine sweat gland complexes; lower left in the picture), superficial and deep lymphocytic infiltrate. Focal epitheliotropy is recognizable (upper left in the picture) in atrophic surface epithelium (reteleases are missing). distinct, plexus-like orthohyperkeratosis; follicles are missing in the present section.
Lupus erythematodes chronicus discoides, detail enlargement: Hydropic degeneration in the stratum basale, lymphocytic infiltrate.
Lupus erythematosus chronicus discoides, follicular hyperkeratosis, histological correlation to the wallpaper-nail phenomenon.
Lupus erythematodes chronicus discoides. direct immunofluorescence (DIF): band-shaped IgG deposits (arrows) at the dermo-epidermal junction zone. also detectable at the hair follicle epithelium (horizontal arrow).
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