Synonym(s)
Acute X-ray dermatitis
DefinitionThis section has been translated automatically.
Acute dermatitis in the irradiated skin area, which occurs 6-12 days (but also later) after irradiation.
Clinical featuresThis section has been translated automatically.
The clinical symptoms are limited to the irradiation field and can be divided into 3 degrees.
- Grade I: Erythematous stage with dark red erythema. Subsequently diffuse or spotty hyperpigmentation. Temporary blockage of sebaceous gland secretion. Hair loss 3 weeks after irradiation, hair regrowth 4-12 weeks after irradiation.
- Grade II: Bullous stage with inflammatory redness, oedema, blistering, weeping. Irreversible loss of hair, sebaceous glands, nails and sweat glands.
- Grade III: ulcerous stage with primary deep tissue necrosis, painful ulceration, acute x-ray ulcer, poor healing tendency.
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General therapyThis section has been translated automatically.
Long-term control examinations (risk of carcinoma development).
External therapyThis section has been translated automatically.
Symptomatic therapy usually only after completion of the irradiation. If necessary, short-term interruption of the radiation therapy. For grade I, glucocorticoids such as 0.1% mometasone (e.g. Ecural fat cream), 0.25% prednicarbate (e.g. Dermatop cream) or 0.05% betamethasone Lotio R030, astringent powders such as tannin powder(Tannolact). In case of weeping changes and blister formation, moist compresses with antiseptic additives such as quinolinol (e.g. Chinosol 1:1000 or R042 ) or potassium permanganate (light pink). In the case of ulceration, wound treatment appropriate to the stage of ulceration.
Internal therapyThis section has been translated automatically.
Analgesic drugs such as acetylsalicylic acid (e.g. ASS) 3 times/day 500 mg, tramadol (e.g. Tramal Trp.) 20-40 Trp./day, ibuprofen (e.g. Ibuprofen Stada) 200-400 mg/day may be helpful.
Note(s)This section has been translated automatically.
Cytostatic drugs can significantly increase the toxicity of radiotherapy applied a few days before. Radiatio recall is the term used to describe a dermatitis which manifests itself in a previously irradiated area within a few days to hours after initiation of a cytostatic drug therapy.
LiteratureThis section has been translated automatically.
- Prindaville B et al (2016) Radiation Recall Dermatitis Secondary to Dactinomycin. Pediatric Dermatol 33:e278-279.
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Incoming links (9)
Betamethasone valerate emulsion hydrophilic 0,025/0,05 or 0,1 % (nrf 11.47.); Mapisal; Quinolinol sulphate monohydrate solution 0,1 % (nrf 11.127.); Radiation damage; Radiodermatitis; Radiodermatitis chronic; X-ray dermatitis, acute; X-ray surface irradiation; X-ray ulcer;Outgoing links (15)
Acetylsalicylic acid; Betamethasone; Betamethasone valerate emulsion hydrophilic 0,025/0,05 or 0,1 % (nrf 11.47.); Edema; Erythema; Glucocorticosteroids; Hyperpigmentation; Ibuprofen; Potassium permanganate; Powder; ... Show allDisclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer