Synonym(s)
Betamethasone emulsion; Hydrophilic betamethasone valerate emulsion; NRF11.47.
FormulationThis section has been translated automatically.
Rp.
Betamethasone 17-valerate | 0,025/0,05/0,1 | |
Sorbitan monostearate | 2,0 | |
macrogol-8-stearate | 2,0 | |
Medium chain triglycerides | 5,0 | |
glycerol 85% | 5,0 | |
Potassium sorbate | 0,14 | |
Citric acid, anhydrous | 0,07 | |
Aqua purif. | ad | 100,0 |
Hydrophilic, non-ionic betamethasone valerate lotio of type O/W (containing cortisone) for external use. Apply a thin layer initially 2 times/day, then 1 time / day to the diseased skin areas.
Period of use: 6 months
Remark: Betamethasone valerate tends to isomerize in strongly acidic and alkaline environments (Wolf G 2014). The molecule loses about 85% of its effect. Therefore, NRF 11.47. as well as the hydrophilic cream of betamethasone valerate (NRF 11.37.) provides for the addition of a citrate buffer (pH 4.2).
Lit.: Wolf G (2014) Complex interactions between active substance and base. Dermatologist 65: 486-487
Entries in which this recipe is mentioned:
- Bacteride Andrews, pustular
- Betamethasone valerate
- Culicosis
- Dermatitis, Berloque dermatitis
- dermatitis bullosa pratensis
- Dermatitis, exudative discoid lichenoid
- dermatitis herpetiformis
- papulosa juvenilis dermatitis
- Dermatitis, phototoxic
- solar dermatitis
- Dermatosis, acute febrile neutrophilic
- Eczema, photoallergic
- Eczema, post-scabious
- Eczema, seborrhoic
- Embolia cutis medicamentosa
- Erythema exsudativum multiforme
- Erythema gyratum repens
- folliculitis decalvans
- Gamasidiosis
- Granuloma anulare disseminatum
- Granuloma fissuratum
- Hydrophilic betamethasone valerate emulsion 0,05 or 0,1 % (NRF 11.47.)
- Contact urticaria
- lichen sclerosus et atrophicus
- Light dermatosis, polymorphic
- lymphoma, cutaneous T-cell lymphoma, angioimmunoblastic
- melanodermia factitia
- follicular mucinosis
- Plant dermatitis
- prurigo simplex subacuta
- diabetic pruritus
- Pulicosis
- Pustulose, sterile eosinophils
- Pustulose, subcorneal
- pustulosis acuta generalisata
- acute radiodermatitis
- Stevens-Johnson syndrome
- Trombidiosis
- Urticaria pigmentosa bullosa
- Incineration
- Vulva atrophy, primary
- Cellulite, eosinophil