X-ray ulcer L59.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Radium ulcer

Definition
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Deep tissue necrosis after X-ray exposure. An acute 3rd degree x-ray ulcer due to acute toxic radiation damage with primary necrosis is distinguished from a chronic x-ray ulcer that develops due to minor trauma or insufficient oxygen supply to the tissue in the atrophic center of an x-ray orm.

Clinical features
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Chronic x-ray ulcer: Sharply limited ulceration in the centre of an x-ray orm with a yellow, fatty, firmly adherent necrotic coating = x-ray fat. Poor healing tendency.

External therapy
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Stage-specific ulcer therapy, see below wound treatment. Conservative therapy is often lengthy or frustrating.

Internal therapy
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Analgesic drugs like acetylsalicylic acid (e.g. ASS) 3 times/day 500 mg or more effective tramadol (e.g. Tramal Trp.) 20-40 Trp./day. Non-steroidal anti-inflammatory drugs like ibuprofen (e.g. Ibuprofen Stada) 200-400 mg/day may be helpful.

Operative therapie
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Ultima ratio is the excision of the ulcerated area with a tension-free or plastic wound closure.

Literature
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  1. Hagedorn M et al (2003) Long term results of total skin electron beam therapy (TSEBT) in the treatment of mycosis fungoides. dermatologist 54: 256-264
  2. Helmbold P et al (2002) Merkel cell carcinoma. dermatologist 53: 652-658
  3. Panizzion R (1993) Dermato X-ray therapy. Present state. Dermatologist 44: 749-760
  4. Yano K et al (2002) Radiation-induced skin ulcer, cerebral meningioma, and skin cancer following radiation and radium treatment for actinomycosis. Plast reconstr. surgery 109: 2157-2158

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Last updated on: 29.10.2020