Toxic epidermal necrolysis Bilder

Toxic epidermal necrolysis: early stage of toxic epidermal necrolysis with incipient extensive epidermolysis.

Toxic epidermal necrolysis: early stage of toxic epidermal necrolysis with incipient planar epidermolysis. The inlet shows the type of complete detachment of the surface epithelium from its dermal base. Right encircled by several striped red striae distensae.

Toxic epidermal necrolysis. mostly picture of erythema exsudativum multiforme. necrolytic detachment of the skin beginning at the knee and lower leg.

Toxic epidermal necrolysis: incipient extensive necrolytic detachment of the skin.

Toxic epidermal necrolysis. 2 weeks after taking Allopurinol in recurrent attacks of gout, itching and redness on the back for the first time, within a few days dramatic worsening of the general condition with several acute, flat, generalized, randomly distributed, sharply defined, red, weeping and painful erosions. Additional findings were multiple, acute, asymmetrically arranged, disseminated, skin-coloured blisters on a flat erythema on the remaining integument.

Toxic epidermal necrolysis. detailed view of a solitary, acutely occurring, perimamillary, sharply defined, slightly weeping, extensive, erosive detachment of the skin. the sample biopsies showed a vacuum-associated interfacial dermatitis with epidermal keratinocyte necroses.

Toxic epidermal necrolysis. detailed picture: The 67-year-old female patient developed multiple, acute, disseminated, sharply demarcated, partly confluent, soft, skin-coloured blisters on a flat erythema on the entire integument within a few days. In case of persistent fever, antibiotic therapy was initiated.

Toxic epidermal necrolysis: Large, superficial, towel-like detachment of the skin after ingestion of allopurinol.

Toxic epidermal necrolysis. emergency hospitalization of a highly febrile (temp. 39.5 °C) 78-year-old woman with hemorrhagic, areal, epidermal necrolysis in the area of the left arm after ingestion of vancomycin. significantly reduced general condition. it turned out that the patient had received allopurinol and ampicillin for the first time a few days before.

Toxic epidermal necrolysis, detailed picture: hemorrhagic, extensive epidermal necrolysis in the area of the left arm after ingestion of vancomycin.

Toxic epidermal necrolysis: extensive, painful reddening of the palm with blistering.

Toxic epidermal necrolysis: highly acute stage of toxic epidermal necrolysis with the formation of small and large (subepithelial) blisters on unmodified, non-red skin, and the beginning of extensive epidermolysis.

Toxic epidermal necrolysis: highly acute stage of toxic epidermal necrolysis with the formation of small and large (subepithelial) blisters on unaltered, non-red skin (encircled).Further beginning of extensive epidermolysis (edges marked by arrows).Erosive, red area marked by asquare.

Toxic epidermal necrolysis: extensive, painful detachment of the epidermis.

Toxic epidermal necrolysis: Infestation of the eyelids and surrounding area. Toxic epidermal necrolysis after ingestion of Allopurinol.

Toxic epidermal necrolysis. fresh lesion with incipient intrapethelial necrobiotic blistering (upper center of the picture). the epithelium is covered with orthokeratic keratin. the dermis is edematous loosened. loose epidermotropic lymphocytic infiltrate condensed at the dermo-epidermal junction zone.

Toxic epidermal necrolysis. fresh lesion with extensive intrapethelial necrobiotic blistering (upper center of the picture). the epithelium is covered with orthokeratic keratin. the dermis is massively edematous loosened. loose, focal ne condensed, epidermotropic, lymphocytic infiltrate.