Scleroderma systemic Bilder

Scleroderma, systemic. smooth taut facial skin, distinct microstomy with retraction of the upper lip in a young woman.

Scleroderma, systemic. tense facial skin, numerous telangiectasias, conspicuous microstomy, pouch mouth.

Scleroderma, systemic: slightly taut facial skin (see perioral region) distinct perioral fibrosis, which becomes clearly visible when the lips are tapered (see next figure)

Scleroderma, systemic: taut, shiny facial skin (see chin region); distinct perioral fibrosis, which becomes clearly visible when the lips are tapered.

Scleroderma, systemic: within 2-3 years, newly developed telangiectasia of the facial skin.

Scleroderma, systemic: within 2-3 years, newly developed telangiectasia of the facial skin.

Scleroderma, systemic: within a few years, newly developed telangiectasia of the facial skin in previously known systemic scleroderma.

Scleroderma systemic: diffuse sclerotherapy of the gedsammed trunk.

Scleroderma, systemic (sclerosis of the hands): Raynaud's syndrome, known since puberty, palmar hyperhidrosis, slight doughy swellings with reduced skin shifting; sclerosis becomes apparent when the fingers are simply bent.

Scleroderma, systemic (early phase of the disease): recurrent Raynaud's symphotms; high titre of ANA (1:2560); only slight sclerosis of the fingers, onycholysis, slight nail dysrophy, sclerosis of individual cuticles.

Scleroderma, systemic (early phase of the disease): recurrent Raynaud's symphotms; high titre of ANA (1:2560); only slight sclerosis of the fingers, onycholysis (arrows), increased longitudinal striations of individual nail plates, sclerosis of individual cuticles (marked by squares).

Scleroderma, systemic, intermittent Raynaud's syndrome. Due to the sclerosing of the finer points, the fingers become "white" in sections during bending. S.a. flat erythema of the palms.

scleroderma systemic: oedematous swelling of the hands and fingers. when stretching the fingers, white discoloration of the tense skin areas occurs. raynaud's syndrome, known for several years. reduced performance, increased sensitivity to cold, rheumatoid joint complaints, ANA:1:320; SCL70AK+.

Scleroderma systemic: edematous swelling of the hands and fingers. when stretching the fingers, white discoloration of the tense skin areas (see right index finger) occurs. Raynaud's syndrome known for several years. increased sensitivity to cold, rheumatoid joint complaints, ANA:1:620; SCL70AK+.

Scleroderma, systemic. Acute Raynaud's Syndrome with seizure-like "whitening of the fingers."

Scleroderma systemic: sclerodactyly, Raynaud's attack during admission; acral necroses.

Scleroderma, systemic. Raynaud's syndrome (hypothermia and livid discoloration), slight doughy swelling with reduced skin mobility as well as sclerosed cuticles on the right hand of a 50-year-old woman. The phalanx distalis of the index was amputated 2 years earlier due to severe necrosis.

Scleroderma, systemic (calcinosis of the fingertip): circumscribed, perforating, painful calcification foci in the area of an old scar of the index finger tip in a 65-year-old woman.

Systemic scleroderma: Necrosis of the fingertips in long-term known systemic scleroderma.

Systemic scleroderma: complete apical necrosis of the distal phalanx.

Scleroderma systemic: multiple sharply separated fingertip necroses.

Scleroderma, systemic.

Scleroderma, systemic. Hyperkeratotic nail folds with prior bleeding.

Scleroderma, systemic. reflected light microscopic image with hyperkeratotic nail fold, spatter-like hemorrhages.

Scleroderma systemic: enormously widened (marked with a black bar) sclerosed cuticle with megacapillaries (vertical arrow); lacunar hemorrhages (horizontal arrow) in the sclerosed cuticle.

Scleroderma, systemic. Incident light microscopy: megacapillaries in the nail fold.

Scleroderma, systemic. nail fold capillaroscopy, irregularly configured capillaries, chimney-shaped bleeding (in the center of the picture).

Scleroderma, systemic. nail fold capillaroscopy, irregularly configured capillaries, chimney-shaped bleeding (in the center of the picture).

scleroderma systemic: redness and slight blue discoloration (much more pronounced when exposed to cold) of the toes. increased sensitivity to cold. Raynaud's syndrome of the hands, known for several years

Scleroderma systemic necroses Toes_re_3.jpg

differential diagnosis "scleroderma systemic": diagnosis: generalized cGVHD: general ized, scleroderma-like, hardly itching generalized skin disease. graft-versus-host disease occurred about 2 years after stem cell transplantation. poikiloderma with bunchy, hyper- and depigmented indurated plaques.

Scleroderma, systemic. DSA, D3 digital artery dissection.

Scleroderma, systemic. laser Doppler imager; reduced perfusion (blue colour) of the middle finger.

Scleroderma, systemic mechanical extension in pronounced sclerodactyly by means of Mannerfeld splint.

Differential diagnosis "Systemic Scleroderma"-

Generalized GVHD:chronic, generalized, poikilodermatic skin lesions, with circumscribed hardening, atrophy and reticular hyperpigmentation.

Differential diagnosis "Systemic Scleroderma"-

Generalized GVHD: chronic, generalized, poikilodermatic skin lesions, with circumscribed hardening, atrophy and reticular hyperpigmentation.

Scleroderma, systemic. Shapeless widened sclerotic dermis with atrophic eccrine sweat glands and few smooth muscle cell bundles, which are remnants of the atrophic follicular apparatus. Road-shaped fibrosis of the subcutaneous connective tissue.

Scleroderma, systemic. subcutaneous fatty tissue with widened and inflammatory infiltrated septa.