Synonym(s)
DefinitionThis section has been translated automatically.
Podophyllii Rhizoma (off. DAC86, ÖAB90, Ph. Helv.7.) is a mixture of various water-insoluble substances obtained from the ethanolic extract of the rootstock (rhizome+root) of Pophyllum peltatum. They are soluble in 100 T. Ammonia solution, in 10 T. ethanol and partly in ether.
Commission E-Monography: External: pointed condylomas
Experimental medicine: External removal of warts, oncological diseases
IngredientsThis section has been translated automatically.
Ingredients of the extract are the lignans podophyllotoxin and alpha - and beta-peltatine.
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Field of application/useThis section has been translated automatically.
As 10% solution in 90% ethanol locally against Condylomata acuminata. Furthermore extracts were used as laxative (dosage 10-20mg).
ContraindicationThis section has been translated automatically.
Podophyllotoxin has a teratogenic effect. No use in pregnancy!
Trade namesThis section has been translated automatically.
Condylox® solution (apply 2x daily according to doctor's instructions)
Note(s)This section has been translated automatically.
Rhizoma podophyllii is treated with highly diluted hydrochloric acid to obtain podophylline, a highly toxic mixture of substances which is used in ethanolic solution for the treatment of condylomata acuminata.
Podophyllotoxin is a mitosis poison. Derivatives of the podophyllotoxin are introduced as cytostatic drugs (see etoposide, mitoposide, teniposide)
LiteratureThis section has been translated automatically.
- Wenigmann M. (2017) Phytotherapy medicinal drugs, phytopharmaceuticals, application. Urban & Fischer, pp. 109-110
Prof. Dr. med. Peter Altmeyer
Prof. Dr. med. Martina Bacharach-Buhles