Sézary syndrome: 62-year-old patient. 1 year ago first skin changes with uncharacteristic moderately itchy erythema on the trunk and extremities. Findings: Erythroderma with extensive edematous swelling of the skin; massive pruritus; taut lower legs; massive lymph node packages of the groin.
Papillomatosis cutis lymphostatica: massive findings with papillomatous growths on the back of the foot and toes; chronic lymphedema after recurrent erysipelas.
Acromegaly: 43-year-old patient with known acromegaly. Noticeable increase in size of the lower extremities. Simultaneous development of excessive varicosis with consecutive chronic venous insufficiency (CVI).
Striae cutis distensae. older, whitish, differently long and wide, jagged, parallel or diverging atrophic stripes with slightly sunken and thinned skin.
Lichen planus verrucosus. multiple, chronically stationary, unchanged for months, very itchy, up to palm-sized, rough, brownish or brownish-red, verrucous plaques in the area of buttocks and thighs. highly chronic course.
Differential diagnosis of Prurigo nodularis: Lichen planus verrucosus: Isolated and aggregated, massively itchy, scratched papules and nodules in the area of the lower leg (resistance to therapy; progression over years).
Pronounced livedo racemosa: Intermediate findings after 2 more years (period of clinical follow-up over a period of 8 years); few lesions with very painful central necroses.
Angiokeratoma circumscriptum: vascular malformation existing since birth, which has become increasingly prominent in recent years; apart from slight accidental bleeding, no symptoms.
Erythema infectiosum: generalized exanthema with larger and smaller, in its complete manifestation about 3.0 cm in diameter, less symptomatic, on the surface slightly roughened, anular erythema.
Lichen planus exanthematicus. for 2 months persistent, itchy, generalized, dense itchy rash with emphasis on trunk and extremities (face not affected). on the cheek mucosa there are pinhead-sized whitish papules.
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