Results for "psoriasis"

...matologist Louis Jean Brocq is credited with the first description of this entity as "parakeratosis psoriasisformis" in 1921. However, the first case was described by Sabouraud in 1931. The term "parakeratosis...

Parapsoriasis en plaques benign small foci Definition Chronic, idiopathic, small-spotted dermatitis along the cle...

...cytes (HLA-DR, ICAM-1, IP-10), which are held responsible for the interaction with T-lymphocytes in psoriasis, for example.Suppression of epidermal and dermal lymphocyte count and lymphocyte activity (CD3+, CD...

...idermal layers."In case of a dysfunction of the sebaceous glands on the one hand a minus variant of psoriasis or the initiation or the influence of the resident flora of the skin especially by Malassezia spp....

...ing risk factors for both AOID (adult-onset immunodeficiency syndrome) and GPP(generalized pustular psoriasis). Kantaputra P et al. (2021) reported on two unrelated patients with AOID and pustulosis and with G...

...sing risk factors for both AOID(adult-onset immunodeficiency syndrome) and GPP(generalized pustular psoriasis). The skin of patients with GPP and AOID who carry SERPINB3 mutations show overexpression of SERPIN...

...s inflammatory processes and is used to treat flare-ups in adult patients with generalized pustular psoriasis. In the pivotal EFFISAYIL® 1 study, there was a numerical advantage of spesolimab for the GPPASI 75...

...n in the pathogenesis of autoimmune diseases. A Th-17 accentuated inflammatory pattern dominates in psoriasis and rheumatoid arthritis. This specific inflammatory pattern is responsible for the infiltration of...

...mice are susceptible. Note(s) Janus kinase (JAK) inhibitors have demonstrated clinical efficacy in psoriasis in both phase 2 and phase 3 trials and appear to be well tolerated overall (Kvist-Hansen A et al. 2...

...thomechanisms. Representative AiKDs are the different variants of generalized or localized pustular psoriasis. For this heterogeneous group of diseases, mutations/variants in five genes - IL36RN, CARD14, AP1S3...

Calcipotriol Definition Vitamin D3 analogue. Indication Mild to moderate psoriasis vulgaris of the plaque type with an extension of < 30% of the body surface. Dosage and method of...

...ds specifically to chemokine receptor 10 (CCR10). The CCR10 receptor is expressed by lymphocytes in psoriasis. Studies on a similar mouse protein suggest that these protein-receptor interactions may play a cen...

...d, if necessary, the entire integument should be examined (e.g. in atopic diseases and in suspected psoriasis). If the vulva is to be assessed in more detail, vulvoscopy is recommended, which allows examinatio...

...ns have also been described in M.Darier, pityriasis rubra pilaris, mycosis fungoides, erythrodermic psoriasis, M. Grover . Some cases have been observed during treatment with vemurafenib and other biologics. O...

...lizumab. JDDG 9: 834Farewell M et al (2003) A novel target T-cell modulator, Efalizumab, for plaque psoriasis. N Engl J Med 349: 2004-2013Merckserono (2009) Important announcement. Drug safety. germany @mercks...

...a mycological exclusion diagnosis is recommended.If the clinical picture indicates the presence of psoriasis, histological confirmation of the diagnosis should be sought, as this is essential for long-term tr...

...Henoch purpura (Mani LY et al. 2015). Complicatively, IgA nephropathy (IgAN) may be associated with psoriasis (often severe) (Garces CC et al. 2021). Laboratory Non-selective proteinuria (usually <3g/day) a...

...ase, the presence of extra-articular manifestations or rheumatoid factor (RF) and family history of psoriasis or HLA-B27-associated diseases, six defined JIA categories are distinguished, including oligoarthri...

...NF-α and thus prevent the release of IL-1 and IL-6. They are used to treat chronic diseases such as psoriasis vulgaris, psoriasis arthropathica, rheumatoid arthritis, Crohn's disease. Cytokine antibody (usteki...

...complexed with IL-20R2. Occurrence It has been shown that IL-22 is involved in the pathogenesis of psoriasis. For example, IL-22 can inhibit the differentiation of keratinocytes and induced psoriasis-like cha...

...pidermis.Thus, deletion of two members, LCE3B and LCE3C (LCE3B/C-del) has been shown to be a common psoriasis risk factor that interacts with the major psoriasis risk gene HLA-C*06. LCE3A is directly adjacent...

...-25, all of which are essential for lymphocyte homing. Therapy LFA1 antibodies for the treatment of psoriasis: For example, efalizumab, a humanized antibody fragment that specifically blocks the α-subunit of L...

...itchy nodules and lumps Pityriasis rosea (exanthematic with eczematoid scaling, primary medallion) Psoriasis guttata (exanthematic with characteristic scaling, often accompanied by infection)Eczematid-like pu...

...lls and CD8+ cytotoxic cells. It has broad significance in inflammatory pathogenetic pathways (e.g. psoriasis, the systemic scleroderma). In psoriasis, LL-37 is upregulated. In wound healing, the antimicrobial...

...ymmetric (zoster; nevus flammeus, cutaneous mosaics; other skin infections)preferentially extensor (psoriasis vulgaris)preferentially flexural (atopic eczema, lichen (ruber) planus)arranged in the Blaschko lin...