Sinensitin

Methylated flavone derivative that is contained, for example, in Orthosiphonis folium, the cat's beard, and in orange oil. Experimental studies have shown that sinensitin and the flavone derivative eupatorin (also found in Orthosiphon stamineus extracts) have anti-inflammatory properties. Antiproliferative and antiangiontic effects have also been demonstrated for sinensitin.

1. Dolečková I et al (2012) Antiproliferative and antiangiogenic effects of flavone eupatorin, an active constituent of chloroform extract of Orthosiphon stamineus leaves. Fitoterapia 83:1000-1007.
2. Laavola M et al (2012) Flavonoids eupatorin and sinensetin present in Orthosiphon stamineus leaves inhibit inflammatory gene expression and STAT1 activation. Planta Med 78:779-786.
3. Mohamed EA et al (2011) Antihyperglycemic effect of orthosiphon stamineus benth leaves extract and its bioassay-guided fractions. Molecules 16:3787-3801.