Sinensitin

Methylated flavone derivative contained in e.g. Orthosiphonis folium, the cat's beard, and in orange oil. In experimental approaches it could be proven that sinensitin as well as the flavone derivative eupatorin (also detectable in Orthosiphon-stamineus extracts) have anti-inflammatory properties. For sinensitin,antiproliferative and antiangionetic effects have also been demonstrated.

1. Dolečková I et al (2012) Antiproliferative and antiangiogenic effects of flavone eupatorin, an active constituent of chloroform extract of Orthosiphon stamineus leaves. Fitoterapia 83:1000-1007.
2. Laavola M et al (2012) Flavonoids eupatorin and sinensetin present in Orthosiphon stamineus leaves inhibit inflammatory gene expression and STAT1 activation. Planta Med 78:779-786.
3. Mohamed EA et al (2011) Antihyperglycemic effect of orthosiphon stamineus benth leaves extract and its bioassay-guided fractions. Molecules 16:3787-3801.