Eupator

Methylated flavone derivative contained e.g. in Orthosiphon stamineus and in orange oil. Experimental studies have shown that eupatorin and the flavone derivative sinensitin (also found in Orthosiphon stamineus extracts) have anti-inflammatory, anti-proliferative and vascular relaxant properties.

1. Dolečková I et al (2012) Antiproliferative and antiangiogenic effects of flavone eupatorin, an active constituent of chloroform extract of Orthosiphon stamineus leaves. Fitoterapia 83:1000-1007.
2. Laavola M et al (2012) Flavonoids eupatorin and sinensetin present in Orthosiphon stamineus leaves inhibit inflammatory gene expression and STAT1 activation. Planta Med 78:779-786.
3. Mohamed EA et al (2011) Antihyperglycemic effect of orthosiphon stamineus benth leaves extract and its bioassay-guided fractions. Molecules 16:3787-3801.