Type I neurofibromatosis, peripheral type or classic cutaneous form. massive tumorous transformation of the skin with numerous generalized distributed, soft, skin-colored, partly pointed conical shaped neurofibromas on the left mamma. the CT examination (skull) did not reveal any pathological findings. no neurofibromas known in the family.
melanoma, malignant, amelanotic. for years in the region of the right dorsal lower leg localized (61-year-old man), slowly progressing in size, symptomless plaque measuring 1.5 x 2 cm, with coarsely lamellated scaling. the coloration is mainly red, only focally dark brown. the lower part of the tumor is flat-nodularly raised.
Keratocanthoma centrifugum marginatum: Plate-like, centrally ulcerated giant keratoakanthoma over the sternum, persisting for about 8 months, with considerable light damage.
Acne vulgaris (overview): recurrent, multiple, disseminated standing retention cysts of 0.3-1.2 cm size on the back of a 38-year-old mansince adolescence; multiple black comedones (blackheads) are also present.
Prurigo simplex subacuta: typicalpattern of distribution with differently sized, always centrally scratched papules. 0.1-0.2 cm red papules appeared initially, which are centrally eroded in the earliest stages of development. Gradual growth of the area with ulcerated centre and bright red edge margin. Severe, always punctual itching (stimulus response: spooning out of the lesion with the fingernail; then sudden cessation of itching).
Collagenosis, reactive perforating p apules: first appeared about 8 months ago, itchy papules with central depression and hyperkeratotic clot, no known underlying disease.
Mycosis fungoides tumor stage: Mycosis fungoides has been known for years, for about 3 months there have been intermittent attacks of less symptomatic plaques and nodules
Metastasis: Chronically active, rapidly growing, hemispherically protruding, well-defined to the side and depth, symptom-free, red, smooth nodule (melanoma metastasis).
Collagenosis, reactive perforating. detail enlargement: solitary, 0.3-1.3 cm large, red papules with a coarse central horn plug. the smaller papules correspond to an early stage of the disease.
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