Melanoma, malignant, acrolentiginous. 13 x 10 mm large, extensive, black pigmented tumor of the subungual space and distension of the nail bed of the left big toe in a 61-year-old female patient. Advanced stage with nail destruction.
Differential diagnosis of melanonychia: In figure V the arrow points to the pigmentation of the nail fold (Hutchinson sign), which is important for the differential diagnosis.
Epidermodysplasia verruciformis. 34-year-old female patient has had partly erythematous, partly brownish, hyperkeratotic papules in the area of the upper arms and hands since childhood; for some years now, there has been a two-dimensional confluence of the skin changes with complete spread to the palms of the hands. Currently, on both palms (also on the back of the hands and the sides of the fingers) there are partly individual, partly aggregated papules, which are aggregated on the palms to form a large, red, wart-like rough plaque.
Myzetome: Indolent, chronic granulomatous infection of the skin and subcutis with circumscribed, pseudotumorous swellings and fistula formation ("Madura foot"), here marginal zone with a lip formation bordering on healthy skin.
Papillomatosis cutis lymphostatica: massive findings with papillomatous growths on the back of the foot and toes; chronic lymphedema after recurrent erysipelas.
Granuloma eosinophilicum faciei: Very discreet, symptom-free, flat plaque that has existed at this site for 0.5 years. 42 years of otherwise healthy male.
Lentigo of the mucosa: harmless lentigo of the labia minora, persisting unchanged for several years, irregular and blurred, symptom-free, brown-black lentigo of the labia minora (detailed picture) .
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