Tuberous sclerosis. brownish-red angiofibroma (so-called adenoma sebaceum) paranasal on both sides in a 12-year-old boy. first freckle-like changes in the area of the nasal passages and cheeks occurred at the age of 3 years. so far age-related development.
Bourneville-Pringle Phacomatosis, splashlike white spots on the skin, so called ash leave macules, a rather discreet café au lait spot on the inner side of the thigh, which also appears in a less conspicuous form on the extensor side of the thigh.
Tuberous sclerosis, reflected light microscopy: In the centrofacially localized "Adenoma sebaceum" there are multiple sebaceous gland follicles (yellowish colouring) surrounded by telangiectasia and connective tissue as well as several vellus hairs.
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