FibrofolliculomaD23.L
DefinitionThis section has been translated automatically.
Very rare, benign epithelial adnexal tumor of the skin with follicular differentiation, originating from connective tissue and epithelial parts of the hair shaft.
ManifestationThis section has been translated automatically.
Mainly occurring in adulthood.
Clinical featuresThis section has been translated automatically.
Multiple, very rarely solitary, 2-5 mm large, yellowish-white, firm papules, usually in combination with other tumors originating from the hair shaft connective tissue (e.g. trichodiscoma in Birt-Hogg-Dubé syndrome) or with a connective tissue nevus.
HistologyThis section has been translated automatically.
Sharply defined tumour located in the dermis with numerous thin strands anastomosing with each other and extending from the upper part of the follicular epithelium, which may also contain small sebaceous gland parts. These epithelial strands protrude finger-shaped into a thick mantle of basophilic, mucoid, connective tissue stromas.
Differential diagnosisThis section has been translated automatically.
TherapyThis section has been translated automatically.
If necessary, excision (without safety distance).
LiteratureThis section has been translated automatically.
- Gotz G et al (2001) Multiple fibrofolliculomas. Dermatologist 52: 824-827
- Hey K et al (1996) Multiple fibrofolliculomas and glandular cysts of the stomach. Act dermatol 22: 71-73
- Kupres KA et al (2003) Numerous asymptomatic facial papules and multiple pulmonary cysts: a case of Birt-Hogg-Dubé syndrome. Cutis 72: 127-131
- Weintraub R et al (1977) Multiple fibrofolliculomas (Birt-Hogg-Dubé) associated with a large connective tissue naevus. J Cutan Pathol 4: 289-299