TrichofolliculomaD23.L
Synonym(s)
DefinitionThis section has been translated automatically.
Benign, slowly growing, epithelial tumor of the hair follicles. S.a. Adnexal tumors with hair follicle differentiation.
LocalizationThis section has been translated automatically.
Clinical featuresThis section has been translated automatically.
Up to 1 cm large, usually skin-coloured, solid tumour with a central porus from which individual hairs can protrude. The clinic is uncharacteristic. Mostly histological random finding.
HistologyThis section has been translated automatically.
One or more dilated hair follicles, which are surrounded by smaller follicles in a radial pattern. The central, mostly dilated hair follicles contain horn material or vellus hairs. Occasionally also sebaceous gland lobules. Strong, cell-rich fibrous stroma. The " sebaceous gland hamartoma, follicular, cystic" described by Kimura is a disease of the sebaceous gland. The "sebaceous trichofolliculoma" described by Kimura is regarded by various authors as a variant of the trichofolliculoma, as is the "sebaceous trichofolliculoma" described by Plewig, which shows an accentuated differentiation of the sebaceous glands.
Differential diagnosisThis section has been translated automatically.
TherapyThis section has been translated automatically.
LiteratureThis section has been translated automatically.
- Hartschuh W et al (1999) Immunohistochemical investigation of the different developmental stages of trichofolliculoma with special reference to the Merkel cell. At J Dermatopathol 21: 8-15
- Haustein UF (1966) Remarks on the differential diagnosis and histogenesis of trichofolliculoma (hair follicle nevus) Arch Klin Exp Dermatol 226: 199-211
- Lee S, nose man T (1971) Trichofolliculoma dermatologist 22: 165-167
- Kurokawa I et al (2003) Trichofolliculoma: case report with immunohistochemical study of cytokeratins. Br J Dermatol 148: 597-598
- Plewig G (1980) Sebaceous trichofolliculoma. J Cutan Catholic 7: 394-403