Hamartoma, neurofollicularQ85.8
DefinitionThis section has been translated automatically.
Very rare adnexal tumor with hair follicle differentiation.
LocalizationThis section has been translated automatically.
Face, nose.
Clinical featuresThis section has been translated automatically.
Solitary occurring, skin-coloured, firm, 0.3-0.7 cm large papules. Clinically uncharacteristic. Random histological findings.
HistologyThis section has been translated automatically.
Abnormally hyperplastic sebaceous gland-hair unit embedded in a broad fibromyxoidal stroma with interspersed S100 positive cells, cells expressing neuron-specific enolase and synaptophysin, as a sign of neurogenic differentiation.
Differential diagnosisThis section has been translated automatically.
LiteratureThis section has been translated automatically.
- Barr RJ et al (1989) Neurofollicular hamartoma: a light microscopic and immunohistochemical study. J Cutan Pathol 16: 336-441
- Sangueza OP et al (1994) Neurofollicular hamartoma. A new histogenetic interpretation. At J Dermatopathol 16: 150-154
- Nova MP et al (1991) Neurofollicular hamartoma. A clinicopathological study.Am J Dermatopathol 13: 459-462
- Xie DL et al (1999) Neurofollicular hamartoma with strong diffuse S-100 positivity: a case report. At J Dermatopathol 21: 253-255