Angiosarcoma of the head and face skin Bilder

angiosarcoma of the head and facial skin. for several years (!) increasing, so far completely asymptomatic, blurred, red spots on cheeks and forehead in a 75-year-old man. medical consultation because of recurrent, extensive bleeding in lesional skin. since one month growth of a soft, 8 mm large, solid blue-black node in the middle of the cheeks. extensive, configured redness with bizarre, linear and reticular telangiectasia. bleeding in the zygomatic bone.

Angiosarcoma of the skin of the head and face. flat, smooth, asymptomatic, chronically dynamic, slowly growing, red plaques without epidermal involvement in a 68-year-old man.

Angiosarcoma of the head and facial skin. slow, chronic progression without subjective complaints. initially contusiform, blue-red discolored skin, later angiomatous nodules and the development of multiple satellite metastases.

Angiosarcoma of the head and facial skin: the 69-year-old patient noticed this rapidly growing and recurrently bleeding 3x5 cm large, little symptomatic node around the capillitium for 6 months. After incomplete preliminary surgery within a few weeks formation of the present recurrent node. The inconspicuous erythema around the node is noticeable. After the micrographically controlled surgery, the tumor was only free of tumor after an approximately 10 x 10 cm large excision.

Angiosarcoma of the head and facial skin: the 69-year-old patient noticed this rapidly growing and recurrently bleeding 3x5 cm large, little symptomatic node around the capillitium for 6 months. After incomplete preliminary surgery within a few weeks formation of the present recurrent node. The inconspicuous erythema around the node is noticeable. After the micrographically controlled surgery, the tumor was only free of tumor after an approximately 10 x 10 cm large excision.

Angiosarcoma of the head and facial skin: the 69-year-old patient noticed this rapidly growing and recurrently bleeding 3x5 cm large, little symptomatic node around the capillitium for 6 months. After incomplete preliminary surgery within a few weeks formation of the present recurrent node. The inconspicuous erythema around the node is noticeable. After the micrographically controlled surgery, the tumor was only free of tumor after an approximately 10 x 10 cm large excision.

Angiosarcoma of the head and facial skin. punch biopsy of black nodule in the patient described above. epidermis o.B., orthokeratosis, in the middle and deep corium convolute of densely packed, CD31 positive tumor cells. skin appendages largely intact (in the center longitudinally incised hair follicle). below the surface epithelium infiltrate-free zone; here numerous dilated (neoplastic?) vessels (clinical: telangiectasia).

angiosarcoma of the head and facial skin. detail enlargement from previous figure. bizarrely configured, partly solid, partly vasoformatively differentiated, neoplastic CD31 positive tumor convolutes. erythrocyte cluster intra- and extraluminally. numerous nuclear atypes.

Angiosarcoma of the head and facial skin (finding of the clinically presented solitary node): cluster of atypical, irregularly expanded, capillary-like structures partially filled with erythrocytes and lined by irregularly enlarged endothelia, which anastomose with each other. The endothelia show enlarged chromatin-rich nuclei and in places protrude button-like into the lumina. Isolated, they float solitary, also in groups in the lumina. In places the endothelial lining is completely missing. High proliferative activity demonstrable.