Results for "psoriasis"

...phase III studies (CIMPASI-1/-2 as well as CIMPACT), for the treatment of moderate-to-severe plaque psoriasis (Gottlieb AB et al. 2018). In the CIMPACT trial, the PASI 75 at week 12 of therapy under 200mg was...

...ultiforme in the wake of reactivated herpes simplex Pityriasis rosea (classic form) Guttate type of psoriasis vulgaris (in 3% of psoriatic patients, both as a flare-up reaction or as a worsening of the existin...

...pro-inflammatory cytokines.Such mutations are also found in about 80% of sporadic cases of pustular psoriasis without additional manifestations of psoriasis vulgaris. In contrast, IL-36RN gene mutations are on...

...forms not infrequently progress to erythroderma. Frequent deterioration in summer (important DD to psoriasis vulgaris) and marked improvement (until healing) in the cold seasons.Pityriasis rubra pilaris types...

...Although the skin changes have a psoriasiform pattern, there is no etiopathogenetic relationship to psoriasis. In rare cases, M. Grover-like manifestations may occur (Hofmann J et al. 2025). Classification Acc...

PSORS15 Definition PSORS15 (PSORS15 stands for: Psoriasis Susceptibility 15) is a genetic locus associated with psoriasis. The gene is located on chromosome...

...ants have been associated with autoimmune diseases in Europeans. These include:type I diabetes (T1D)psoriasismultiple sclerosis andhyperimmunoglobulin E syndrome (HIES; primary immunodeficiency with elevated I...

...ation of 112 days. Field of application/use Approved for the treatment of moderate to severe plaque psoriasis in adults in whom other basic therapies (e.g. MTX, cyclosporine, fumarates, PUVA) have failed to re...

...used as monotherapy if MTX is intolerable.It has now also been approved as a first-line therapy for psoriasis.Plaque psoriasisAdalimumab can also be used in children with severe plaque psoriasis who have not r...

...n mast cells, neutrophil granulocytes, monocytes and T-cells. LL-37 acts as a Z-cell autoantigen in psoriasis. Dermcidins (DCD) are antimicrobial peptides that are produced in human sweat glands and excreted t...

...o make a diagnosis of psoriatic arthritis, patients must fulfill the following criteria:Presence of psoriasis: There must be a documented history of psoriasis or clinical signs of psoriasis. This can be a posi...

...). Erythema anulare centrifugum does not exhibit distinct fissure lines. Erythema anulare-like psoriasis: Typical (annular) plaque psoriasis is a very important differential diagnosis. Like erythema anula...

...ly and has been available as a first-line therapy for adult patients with moderate to severe plaque psoriasis since November 2017. Field of application/use Data from the VOYAGE 1 study showed significant impro...

...l information There is good evidence that LCE proteinsplay an important role in the pathogenesis of psoriasis . Terminally differentiating epidermal keratinocytes express a large number of structural and antim...

...mationLCE3A protein/ LCE3A geneLCE3B protein/ LCE3B gene /wound response/LCE3C protein/ LCE3C gene /psoriasis-associated/LCE3D protein/barrier repairLCE3E protein/ antimicrobialThe LCE3-3E can be described as...

...ines include:AdiponectinC1q/tumor necrosis factor-related protein (CTRP) Pathophysiology Leptin and psoriasis:Leptin is a hormone produced by the WAT that regulates appetite and energy balance. Its level is re...

...dactylitis; Fingertip pustulation; Hjorth-Sabouraud disease; Hjorth-Sabouraud Erkrnakung; Keywords Psoriasis-like parakeratosis; onycholysis;   History The French dermatologist Louis Jean Brocq is c...

PSORS6 Definition PSORS6 (PSORS6 stands for psoriasis susceptibility locus 6) is a psoriasis susceptibility locus located in chromosomal region 19p13. Li...

PSORS9 Definition PSORS9 (PSORS9 stands for psoriasis susceptibility locus 6) is a psoriasis susceptibility locus located in chromosomal region 4q28-32....

...coccal infections can trigger flare activity.The relationship between PPP and pustular palmoplantar psoriasis is the subject of research. Research results indicate a possible common genetic and immunological b...

...ed to as Reiter's tetrad! Oligosymptomatic courses are not uncommon. The relationship to (pustular) psoriasis is controversial. Occurrence/Epidemiology Incidence: 3-5/100,000 population/year. The incidence aft...

...on reactions after organ transplantation; for the treatment of autoimmune diseases, severe forms of psoriasis vulgaris and psoriatic arthritis.Topical: Moderate to severe atopic eczema, see under Eczema, atopi...

...IG-3 (Tazarotene induced gene 3) coding sequences. Indication Approved indication: mild to moderate psoriasis vulgaris of the plaque type, see isotretinoin below. Newer non-approved indications are actinic ker...

...ociated with a lower risk of a variety of autoimmune diseases. Associations with hypothyroidism and psoriasis were confirmed in MR analysis of tissue-specific TYK2 gene expression, and associations with system...

...hibit ribonuclease P (RNase P) to varying degrees depending on the dose. Indication Severe forms of psoriasis vulgaris, pustulosa generalisata, pustulosa palmaris et plantaris, lichen planus, ichthyosis, subco...