Vitis viniferae folium rubrum

Last updated on: 05.03.2025

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Definition
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Leaves of the red vine.

Currently no pharmacopoeial quality description.

HMPC monograph: Internal: well established use: chronic venous insufficiency (CVI), leg swelling, varicose veins, heavy, aching and tired legs, itching and tightness in the calves, calf cramps. External: traditional-use: venous circulatory disorders, burning and itching with haemorrhoids; skin capillary fragility (spider veins).
ESCOP monograph: chronic venous insufficiency (CVI), haemorrhoids;
Commission E: not processed

Pharmacodynamics (Effect)
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Antiphlogistic, antiexudative, anti-edematous, capillary-sealing, endothelial-protective, membrane-stabilizing, antioxidant, improvement of microcirculation, inhibition of platelet aggregation, inhibition of hyaluronidase and elastase.

Dosage and method of use
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Finished medicinal product: see package leaflet.


Tea infusion: one cup 2 to 3 times daily; daily dose 10 to 20 g drug.

[Pour approx. 150 mL of boiling water over 3 to 6 g of finely chopped red vine leaves and strain after 10 to 15 minutes].

Undesirable effects
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Headache, skin reactions, rarely gastrointestinal symptoms.

Preparations
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Antistax® vein tablets, Antistax® extra vein tablets, Antistax® vein capsules, Antistax® vein cream

Note(s)
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Ingredients: flavonoids with the main representative quercetin-3O-beta-glycoside, anthocyanins, tannins, phenolic carboxylic acids tatrate, tartaric acid, malic acid, succinic acid.

Literature
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  1. https://arzneipflanzenlexikon.info/weinrebe.php
  2. https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-vitis-vinifera-l-folium-first-version_en.pdf
  3. Wenigmann M.(2017) Phytotherapie Arzneidrogen Phytopharmaka Anwendung.Urban & Fischer: 5.120 Weinlaubblätter, Rote (Vitis viniferae folium) S 212-213
  4. Kiesewetter H et al. (2000) Efficacy of orally administered extract of red vine leaf AS 195 (folia vitis vinifera) in chronic venous insufficiency (stages I-III). A randomized, double blind, placebo-controlled trial. Drug research 50: 109-117

Last updated on: 05.03.2025