Ruta graveolentis herba

Authors:Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 10.06.2024

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Synonym(s)

Diamond cabbage; Garden herb; Lozenge oil; Rue de vine

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DefinitionThis section has been translated automatically.

Medicinally used herb of Ruta graveolens the garden rue. Ruta graveolentis Herba is the starting product of Oleum Rutae the rue oil, which is obtained by steam distillation of the herb.

IngredientsThis section has been translated automatically.

0,2-0,7 % essential oil (in fresh herbs 0,06-0,09 %) with methyl ketones and their carbinols or carbinyl acetates; furthermore rutin, bergapten, psoralen, as well as various alkaloids Herb and oil contain the coumarin derivatives rutamarin, gravelliferone, daphnoretin and daphnoretin methyl ether.

Root extracts contain the furanocoumarins bergapten, isopimpinellin, rutamarin and xanthotoxin.

EffectsThis section has been translated automatically.

Spasmolytic, abortive, phototoxic, virostatic, antibacterial, insecticidal.

Preliminary reports of antitumour effects of extracts of garden herb are to be considered as preliminary.

Field of application/useThis section has been translated automatically.

Use as an antispasmodic, emmagogue. Ophthalmologically, it is used for "red eye" and "eye fatigue". In this case we recommend e.g. Ruta D3 Weleda

Undesirable effectsThis section has been translated automatically.

Diamond oil can lead to contact dermatitis in humans. Phototoxic reactions in the sense of the development of light dermatoses have also been described. Severe liver and kidney damage caused by rue oil has also been documented. The furanocoumarins contained in the drug have a phototoxic and mutagenic effect.

Note(s)This section has been translated automatically.

  1. Freyer G et al (2014) Open-label uncontrolled pilot study to evaluate complementary therapy with Ruta graveolens 9c in patients with advanced cancer. Homeopathy 103:232-238.
  2. Jeon JH et al (2015) Isolation of Insecticidal Constituent from Rutagraveolens and Structure-Activity Relationship Studies against Stored-Food Pests (Coleoptera). J Food Prot 78:1536-1540.
  3. Klosa R et al (1987) Ruta graveolens - The garden rue. Zschr. f. Phytother 8: 202-206.
  4. Loonat F et al (2014) Antinociceptive, anti-inflammatory and antipyretic activities of the leaf methanol extract of Ruta graveolens L. (Rutaceae) in mice and rats. Afr J Tradit Complement Altern Med 11:173-181.
  5. Minker, E. et al (1979) Pharmacological study of the antispasmodic principles isolated from Ruta graveolens L.. Planta medica 36: 255-256
  6. Novák I et al.(1967) Investigation of the active ingredients of Ruta graveolens L.. Planta medica 15: 132-139.
  7. Saeidinia A et al. (2016) Lack of antibacterial activity of Ruta graveolens extracts against Enterococcus fecalis. Pak J Pharm Sci 29(4 Suppl):1371-1374.
  8. Sivakamavalli J et al (2014) Discrete nanoparticles of ruta graveolens induces the bacterial and fungal biofilm inhibition. Cell Commun Adhes 21:229-238.

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Last updated on: 10.06.2024