Iberis amara totalis

Iberis amara totalis, also known as bitter mustard, is the ethanolic-aqueous extract of the entire plant(Iberis amara totalis). This drug from the parent plant Iberis amara L. is used in herbal medicines to treat gastrointestinal disorders, among other things.

Not only the herb of the plant is used but also the seeds.

HMPC: not processed

ESCOP: not processed
Commission E: not processed

not on the market as a single preparation, only in a finished medicinal product (combination with angelica root, camomile flowers, caraway fruits, milk thistle fruits, lemon balm leaves, peppermint, celandine and licorice root; ^Iberogast®)

Iberis amara totalis contains glucosinolates, including glucoiberin, glucocheirolin, glucoibervirin. Other ingredients are flavonoid glycosides, amines and traces of cucurbitacins E, K, I.

Farmer's mustard has spasmolytic, inflammatory, anti-ulcerogenic effects and also has a toning effect on the smooth muscles of the stomach and small intestine.
The anti-ulcerogenic effect is produced by reducing acid secretion and leukotriene concentration while simultaneously increasing mucin secretion and prostaglandin E2 concentration.

Iberis amara totalis is used in motility related gastrointestinal disorders with spasms, functional dyspepsia, gastroesophageal reflux, non-ulcer gastritis and irritable colon. Traditional indications also include soft tissue rheumatism, irritable stomach and the feeling of fullness.

The usual daily dose is 0,45 to 0,90 ml of ethanolic-aqueous fresh plant extract from the whole plant. It is taken in combination with other plant gastrointestinal remedies such as camomile flowers, peppermint leaves and liquorice root.

At a maximum content of 200 ug total cucurbitacine and 150 ug glucoiberin no adverse effects are known.

Allergy to one of the ingredients

1. Melzer J etal.(2004) Iberis amara L. and Iberogast--results of a systematic review concerning functional dyspepsia. J Herb Pharmacother 4:51-59.
2. Reichling J et al. (2002) Iberis amara L. (bitter candytuft)--profile of a medicinal plant. Forsch Komplementarmed Klass Naturheilkd 9 Suppl 1:21-33.
3. Schilcher H (2016) Leitfaden Phytotherapie, Urban & Fischer Verlag Munich, p. 69 f.
4. https://arzneipflanzenlexikon.info/schleifenblume.php