Caryophilli flos

Authors:Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

All authors of this article

Last updated on: 18.07.2021

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Synonym(s)

Carnations; Cloves; Flores Caryophyllii; Nails

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DefinitionThis section has been translated automatically.

Medicinally used constituents of dried flower buds of the clove tree. Caryophilli flores is the subject of Commission E and WHO monographs, see Caryophylli floris aetheroleum.

IngredientsThis section has been translated automatically.

The active ingredients of Caryophylli flos are different amounts of essential oil (Ph.Eur.8 minimum 15%) with about 85-95% eugenol as main component, 3% oleanolic acid (caryophylline a triterpene apogenin), 6-12% fatty oil, tannins, flavonoids and small amounts of vanillin.

EffectsThis section has been translated automatically.

antiseptic, antibacterial, antifungal, antiviral and local anesthetic.

DosageThis section has been translated automatically.

As a stomachic, Caryophilli flos 1-5% is used as mouthwash. In dentistry clove oil is used undiluted for root canal fillings.

In folk medicine it is used for insect bites.

Undesirable effectsThis section has been translated automatically.

The ingredients of cloves, eugenol and isoeugenol play a major role as allergens. Sensitizing potency: Medium strength. Frequency of sensitization: Occasional. Sensitization ( contact allergy; urticaria) is mainly found on dental material by dental staff. Cross-reactivity exists to Peru Balsam.

Trade namesThis section has been translated automatically.

Repha-Os® Mouth spray, Salviathymol® drops

LiteratureThis section has been translated automatically.

  1. Adefegha SA et al (2014) Antihyperglycemic, hypolipidemic, hepatoprotective and antioxidant effects of dietary clove (Szygium aromaticum) bud powder in a high-fat diet/streptozotocin-induced diabetes rat model. J Sci Food Agric 94: 2726-2737
  2. Dibazar SP et al (2014) Immunomodulatory effects of clove (Syzygium aromaticum) constituents on macrophages: in vitro evaluations of aqueous and ethanolic components. J Immunotoxicol 12: 124-131
  3. Geier J et al (2016) News on the epicutaneous test series of the German Contact Allergy Group. Dermatology at work and in the environment 64: 70-75
  4. Hausen BM, Vieluf K (1997) Allergy plants, plant allergens. Ecomed Publishing House Landsberg/Munich 224-226
  5. Lee JI et al (2001) Purification and characterization of antithrombotics from Syzygium aromaticum (L.) Merr. & PERRY. Biol Pharm Bull 24: 181-187
  6. Mansourian A et al (2014) The comparative study of antifungal activity of Syzygium aromaticum, Punica granatum and nystatin on Candida albicans; an in vitro study. J Mycol Med 24: e163-168
  7. Ranasinghe L (2002) Fungicidal activity of essential oils of Cinnamomum zeylanicum (L.) and Syzygium aromaticum (L.) Merr et L.M. Perry against crown rot and anthracnose pathogens isolated from banana. Lett Appl Microbiol 35: 208-211
  8. Sultana B et al (2015) In vitro antimutagenic, antioxidant activities and total phenolics of clove (Syzygium aromaticum L. seed extracts. Pak J Pharm Sci 27:893-899

Authors

Last updated on: 18.07.2021

Authors: Prof. Dr. med. Peter AltmeyerProf. Dr. med. Martina Bacharach-Buhles