Betulae folium

Authors:Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 02.03.2023

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Synonym(s)

Folia Betulae. birch leaves

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DefinitionThis section has been translated automatically.

Offical preparations of dried, whole or cut foliage leaves of Betula pendulans or Betula pubescens Erhart, or of both species (see birch below) together.

HMPC monograph: traditional use to increase urine production in mild urinary tract problems.

ESCOP monograph: for flushing the urinary tract, especially in urinary tract inflammation and kidney gravel; supportive in bacterial urinary tract infections.
Commission Emonograph: for flushing in bacterial and inflammatory diseases of the draining urinary tract and kidney gravel; supportive in rheumatic complaints.

Empirical medicine: to promote excretion in gout, as a hair tonic for hair loss.

IngredientsThis section has been translated automatically.

EffectsThis section has been translated automatically.

Betulae folium, the birch leaves are official (Fol. Betula) as bladder and kidney tea preparations. A triterpene extract from the outer birch bark with > 80% betulin proved in a non-randomized study to be an anticarcinogenic as efficient as cryotherapy.

Betulin and betulinic acid have antiproliferative (melanoma cells) antibacterial, antimycotic and reverse transcriptase inhibiting effects.

Recipe(s)This section has been translated automatically.

The fixed combination birch leaves+goldrod+orthosiphon leaves consists of

has an anti-inflammatory, slightly antispasmodic effect, promotes urinary excretion and is used as a preventive measure against renal gravel and as part of a flushing therapy for inflammatory diseases of the urinary tract.

Trade namesThis section has been translated automatically.

Bladder Kidney Tea Stada® N, Bladder Kidney Tea Uroflux® vegatable tea, Bladder Kidney Tea Uroflux® tea infusion powder, Buccotean®, Buccotean® TF, Buenoson® N Ointment, Dr. Klinger's Bergisch Bladder and Kidney Tea, Dr. Klinger's Bergischer Blutreinigungs- und Stoffwechseltee, Fugacid® bladder tea, Fugacid® uric acid tea, Hevert bladder and kidney tea, NB-tea Siegfried®, Nephronorm® tea, Nephrubin® tea, Kidney Bladder Tea, Kidney Tea 2000, Nieron® Bladder and Kidney Tea ®, Nieron® Tea N, Renob® Bladder and Kidney Tea (bag), Rheumatism Gout Tea, Röwo-714 AdipoRö-Plax, Solvefort® N, Uro Fink®.

LiteratureThis section has been translated automatically.

  1. Drąg-Zalesińska M et al.(2017) Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45). Cancer Cell Int 17:4.
  2. Guo MY et al. (2015) Betulin suppresses S. aureus-induced mammary gland inflammatory injury by regulating PPAR-γ in mice. Int Immunopharmacol. 29:824-831.
  3. Laavola M et al.(2016) Betulin Derivatives Effectively Suppress Inflammation in Vitro and in Vivo. J Nat Prod 79:274-280.
  4. Laszczyk MN et al. (2009) Regenerative and anti-inflammatory effects of betulin emulsions in impaired epidermal barrier function. Act. Dermatol 35: 1-5
  5. Li Y et al (2016) Betulin induces reactive oxygen species-dependent apoptosis in human gastric cancer SGC7901 cells. Arch Pharm Res 39:1257-1265.Pix betulina.
  6. Viszwapriya D et al.(2016) Betulin inhibits virulence and biofilm of Streptococcus pyogenes by suppressing ropB core regulon, sagA and dltA. Pathog Dis 74 PubMed PMID: 27596811.
  7. https://www.ema.europa.eu/en/medicines/herbal/betulae-folium
  8. https://arzneipflanzenlexikon.info/birch.php.
  9. Wenigmann M. (2017) Phytotherapy medicinal drugs, phytopharmaceuticals, application. Urban & Fischer, pp. 81-82

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Last updated on: 02.03.2023