Neutral gene mutation

Last updated on: 17.05.2023

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Definition
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A neutral mutation causes a different amino acid sequence in the protein. However, the change has no effect on the function of the resulting protein. In fact, in some regions of a protein (variable region), an exchange of amino acids or even a gap formation is possible without resulting in a loss of function.

General information
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A mutation is a permanent change in the genetic material . The following types of mutations are distinguished: gene mutation , chromosome mutation , genome mutation . Mutations can occur spontaneously, e.g. during DNA replication or meiosis. Mutation can also be induced e.g. by mutagens. Induced mutation: Factors outside the cell (mutagens), can also cause mutations. These are, for example, high-energy radiation, such as X-rays or UV radiation, as well as certain chemical compounds or special viruses. The following inheritance patterns are known:

  • Somatic mutation (confined to body cells only).
  • Germline mutations (the mutation is passed on to offspring).

Mutations are divided into the following forms:

  • silent mutation
  • neutral mutation
  • loss-of-function mutation
  • gain-of-function mutation
  • conditional mutation
  • lethal mutation

Last updated on: 17.05.2023