Amyloidosis systemic (overview) Images

AL-amyloidosis in smoldering myeloma. 77-year-old patient with recurrent ecchymosis of the periorbital region, clinically corresponding to a hematoma of the eyeglasses. These characteristic skin lesions are called "raccoon sign". Further purple skin lesions are found in the neck and retroauricularly. The bone marrow biopsy showed a smoldering myeloma (infiltration of plasma cells at 15%).

Amyloidosis systemic of the Al type. after banal efforts or local trauma completely symptomless, permanently persistent purpura. on intensive examination a flat, symptomless discoloration (amyloid deposits) of the anterior neck area is noticeable. known plasmocytoma.

Amyloidosis systemic: Yellow-brown, symptomless plaque in long-term dialysis.

AL-amyloidosis in smoldering myeloma: In the 77-year-old patient, this macroglossia with lingua plicata, which has been steadily increasing for 1 year, is clinically present with recurrent flat ecchymoses of the periorbital region, corresponding to a hematoma of the eyeglasses. Further purple skin changes are present in the neck and retroauricularly. The bone marrow biopsy revealed smoldering myeloma (degree of infiltration of plasma cells at 15%).

Amyloidosis systemic: Red-brown, symptomless papules and plaques. Known HIV infection.

Amyloidosis systemic: Flat light brown, symptomless plaques on both backs of the hands and fingers; recurrent fresh haemorrhages after banal traumas.

Amyloidosis systemic: flat light brown, symptomless spots and plaques on both backs of the hands; recurrent fresh bleeding in the case of banal trauma.

Amyloidosis systemic of the Al type: in relapses, more prominent after physical exertion, completely asymptomatic, permanently persistent purpura on both lower legs in a 65-year-old. Known plasmocytoma.

Systemic amyloidosis: persistent purpura (see legend in previous figure).

Amyloidosis systemic with polyneuropathy and malum perforans.