Amyloidosis systemic: flat light brown, symptomless spots and plaques on both backs of the hands; recurrent fresh bleeding in the case of banal trauma.
Lentigo solaris: multiple, disseminated, a few millimetres to 1.5 cm in size, oval, roundish or bizarrely configured, sharply defined, yellow-brown to dark brown spots on the back of the hand of a 75-year-old man (convertible driver).
Atrophodermia idiopathica et progressiva. chronic stationary, map-like spread, brownish spots. the existing skin changes have developed within 2-3 years.
Purpura pigmentosa progressiva: aetiologically unexplained (medication?) pronounced clinical picture that has been changing for several months with symmetrically distributed, disseminated, non-itching, yellow-brown, spots (detailed picture).
Chloasma. extensive, partly gyriated, diffuse, brownish hyperpigmentation on the right upper arm of a 51-year-old female patient. continuous hormonal anti-conception has existed for about 18 years.
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