Basal cell carcinoma, pigmented basal cell carcinoma, partly nodular, partly growing only in the skin level, with rough consistency, ulceration at the right tumor margin, difficult clinical differentiation to a nodular malignant melanoma.
Lichen myxoedematosus: Densely grouped, skin-coloured, also light-glassy, clearly increased in consistency, hardly itchy, shiny, 0.1-0.2 cm large, non follicular nodules (compare hair follicles and their topographical relationship to the nodules; see also further illustrations). Clear linear arrangement of the nodules.
Reflected light microscopy of a trichoblatoma on the shoulder of a 39-year-old female patient, image from the collection of Prof. Dr. med. Michael Drosner.
Prurigo nodularis. chronically active disease pattern, increasing since 5 years. generalized, disseminated, 0.4-2.0 cm large, very itchy, flatly raised or hemispherically raised, rough, red plaques and nodules. numerous excoriations (scratch artifacts). neck, hands and feet are not affected.
type i neurofibromatosis, peripheral type or classic cutaneous form. since puberty slowly increasing formation of these soft, skin-coloured or slightly brownish, painless papules and nodules. characteristic for neurofibromas are consistency and the bell-button phenomenon (the papules can be pressed into the skin under pressure). on the flanks on both sides large café-au-lait spots up to 8 cm in diameter. the simultaneous detection of several café-au-lait spots secured the clinical diagnosis here.
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