Toxic epidermal necrolysis. detailed view of a solitary, acutely occurring, perimamillary, sharply defined, slightly weeping, extensive, erosive detachment of the skin. the sample biopsies showed a vacuum-associated interfacial dermatitis with epidermal keratinocyte necroses.
Basal cell carcinoma, nodular, centrally ulcerated tumor with a clear wall at the edge of the temporal region. Ulcer not painful. Characteristic for the diagnosis "basal cell carcinoma ulcerated" is the raised, reflecting wall of the "ulcer" with the bizarre vascular structures already visible with the naked eye, which run over the wall (see edge region below right).
Prurigo gestationis: 32-year-old female patient in the 6th month of pregnancy with increasing, severe itching, pruriginous rash; fresh effglorescence is not detectable, only scratched papules.
Lymphomatoid papulosis. reflected light microscopy (detail): In the initial phase of a papule eruption a concentric or radial pattern of punctiform or garland-like vascular ectasia is visible. partially brownish background pigment (oxidative haemoglobin degradation).
Collagenosis, reactive perforating. 12-month-old female patient: Red, solitary, partly confluent, itchy, coarse papules with hyperkeratotic clot on the right lower leg of an 80-year-old female patient.
Zoster ophthalmicus: since 6 days increasing, left-sided headache with accompanying feeling of illness. since 3 days redness and swelling of the skin with stabbing, shooting pain. extensive erythema, blisters, scaly crusts and swelling
Stevens-Johnson syndrome: acute, extensive, painful erosions of the red of the lips, the lip mucosa, the tongue and the gingiva in an 18-year-old woman.
Lichen planus erosivus mucosae. painful gingivitis existing for more than one year in cases of currently unsuccessful therapies by the dentist. overall progressive course. chronically stationary, extensive, border-like, painful erythema and erosions as well as extensive whitish plaques are visible.
Lymphomatoid papulosis: now misdiagnosed as ulcerative "pyoderma". As it was a multiple relapse of the same disease, the diagnosis is clinically confirmed. Previously painless nodular formation within 14 days with rapid (overnight) central necrosis.
Ulcer cruris: Painful ulcer extending to the muscle fascia, with sharp edges and painful ulcer in necrobiosis lipoidica; bizarre vascular ectasia due to the atrophying underlying disease.
Porphyria cutanea tarda: close-up. older scars marked by stars. vertical arrows: encrusted erosions after traumta; vertical arrows: bulging (subepithelial - the entire epidermis forms the firm bladder roof) fresh areactive blisters (the blisters appear as if from nowhere. no signs of inflammation!)
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