Melkersson-Rosenthal syndrome: initially variable, after a few months persistent, unilateral, reddened swelling and induration of the lower lip in a 62-year-old woman. Feeling of tension. No pain.
pachydermoperiostosis, primary: A 32-year-old man of Han Chinese origin presented with a 15-year history of a peculiar facial appearance (Panel A). after puberty, he had noticed a progressive enlargement of his hands and feet as well as facial furrowing. the patient reported that the progression of disease had stabilized by the time he was 27 years of age. on examination, he had excessive sebaceous secretions and thick, furrowed, and redundant skin on his forehead, cheeks, and chinese. soft-tissue hypertrophy reduced the motion of his hands and feet, with terminal broadening of the fingers (Panel B) and toes and cylindrical enlargement of the limbs. the patient received a clinical diagnosis of pachydermoperiostosis, a rare genetic disease characterized by pachyderma, digital clubbing, and periostosis. his parents and son did not have similar symptoms; no genetic testing was performed. the therapy was performed in two stages. in the first stage, we implanted an expander under the patient's forehead skin to enlarg
Graft-versus-Host-Disease: chronic. 1.5 years after stem cell transplantation, large-area, scleroderma skin changes. significant increase of the poikiloderma skin areas in the exposed zones. significant reduction of the AZ
Lichen sclerosus extragenitaler (and genital): generalized, itchy Lichen sclerosus with small and large, partly sharp and partly blurred bordered spots and plaques with parchment-like surface, known for years.
Sclerema adiposum neonatorum: skin and subcutaneous tissue that has existed since birth and is increasingly leathery, waxy pale, cold, non-removable, impairing the mobility of the joints.
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