Synonym(s)
Normolipemic papular xanthomatosis; Papular normolipemic xanthomatosis
DefinitionThis section has been translated automatically.
Generalized xanthomatosis with xanthomas up to smallerbsized without evidence of hyperlipidemia. The disease is classified in the xanthogranuloma family.
ManifestationThis section has been translated automatically.
Only for adults.
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LocalizationThis section has been translated automatically.
Face, trunk, rarely mucous membrane involvement.
Clinical featuresThis section has been translated automatically.
2-15 mm large, yellowish, roundish, maculopapular efflorescences.
HistologyThis section has been translated automatically.
Accumulation of fat-storing foam cells in the upper and middle corium; admixtures of lymphocytes, eosinophilic leukocytes and giant cells.
Electron microscopy: Detection of regularly structured "laminated bodies".
Differential diagnosisThis section has been translated automatically.
TherapyThis section has been translated automatically.
Spontaneous healing possible. If necessary, excision or curettage, ablation with theCO2 laser or with the help of cryosurgery, see below Xanthelasma.
Progression/forecastThis section has been translated automatically.
Variable course with tendency to spontaneous healing.
LiteratureThis section has been translated automatically.
- Breier F et al (2002) Papular xanthoma: a clinicopathological study of 10 cases. J Cutan Pathol 29: 200-206
- Bundino S et al (1988) Papular Xanthoma. Dermatologica 177: 382–385
- Caputo R et al (2003) Papular xanthoma associated with angiokeratoma of Fordyce: considerations on the nosography of this rare non-Langerhans cell histiocytoxanthomatosis. Dermatology 206: 165-168
- Sanchez RL et al (1985) Papular Xanthoma. Arch Dermatol 121: 626-631
- Yoshimura T et al (1994) Generalized normolipemic plane xanthomatosis associated with relapsing polychondritis. Acat Derm Venereol 74: 221-223
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Incoming links (3)
Hypertriglyceridemia familial; Xanthogranuloma necrobiotic with paraproteinemia; Xanthomas papulöse;Outgoing links (13)
Cryosurgery; Curettage; Dermis; Excision; Generalized eruptive histiocytosis; Juvenile xanthogranuloma; Laser; Reticulohistiocytosis multicenter; Xanthelasma; Xanthogranulomas (overview); ... Show allDisclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer