Trichilemmal carcinomaC44.L

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

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Synonym(s)

malignant tricholemmoma; trichilemmoma malignes; Tricholemmal carcinoma

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HistoryThis section has been translated automatically.

Headington, 1976

DefinitionThis section has been translated automatically.

Rare, low malignant carcinoma originating from hair follicles, which histologically mimics tricholemmoma structures, see also Hair follicle tumor.

ManifestationThis section has been translated automatically.

Occurring in old age.

LocalizationThis section has been translated automatically.

Located in chronically light-exposed areas (face, ear, neck).

Clinical featuresThis section has been translated automatically.

Uncharacteristic: Relatively rapidly growing, 0.5-2 cm large, erosive-wetting or crusty, exophytic tumor.

HistologyThis section has been translated automatically.

Infiltrating and destructively growing tumor of lobular, usually well-defined structure of differently sized, bright, optically empty cells with chromatin-tight nuclei. Significant cell and nuclear polymorphism, atypical mitoses. Occasional abortive hair formation.

Differential diagnosisThis section has been translated automatically.

TherapyThis section has been translated automatically.

Surgical removal in healthy people (safety distance about 3 mm).

Progression/forecastThis section has been translated automatically.

Favourable: In the long term only local growth, very rarely metastasis in the regional lymph nodes.

LiteratureThis section has been translated automatically.

  1. Headington JT (1976) Tumors of the hair follicle. A review. On J Pathol 85: 481-514
  2. Misago N et al (2002) Tricholemmal carcinoma in continuity with trichoblastoma within nevus sebaceus. At J Dermatopathol 24: 149-155
  3. Schell H et al (1986) Tricholemmal carcinoma. Dermatologist 37: 384-38
  4. Van Zele D et al (2002) Invasive tricholemmal carcinoma of the nose. Dermatology 204: 315-317

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer