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Inverted follicular keratosisD23.L

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Acrotrichoma; inverted follicular keratosis; Keratosis follicularis inversa

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HistoryThis section has been translated automatically.

Helwig, 1955

DefinitionThis section has been translated automatically.

A benign tumour originating from the infundibular part of the outer hair sheath, which is rare and occurs in the face of elderly people. S.a. Hair follicle tumor.

EtiopathogenesisThis section has been translated automatically.

Among other things, the association with HPV virus infections is discussed.

ManifestationThis section has been translated automatically.

Usually occurring after the age of 50.

LocalizationThis section has been translated automatically.

On the face, preferably located on the upper lip and cheeks, very rarely in unexposed areas.

Clinical featuresThis section has been translated automatically.

Single, coarse, up to 0.3-1.0 cm large, skin-coloured or grey-brown, raised, often crusty, asymptomatic nodule.

HistologyThis section has been translated automatically.

Well defined, papillomatous, epithelial tumor consisting of finger-like tumor formations extending into the upper dermis, consisting of basaloid and squamous cells. In the centre, spiny cells with eosinophilic cytoplasm predominate, which are focally arranged in the shape of onion cups. No cell atypia.

Differential diagnosisThis section has been translated automatically.

Verruca seborrhoica; keratoacanthoma; basal cell carcinoma; dermal melanocytic nevus; verrucae vulgaris; eccrine poroma (Sawaya JL et al. 2014)

TherapyThis section has been translated automatically.

It is a histological random diagnosis. A safety distance of 1-2 mm is sufficient.

LiteratureThis section has been translated automatically.

  1. Headington JT (1976) Tumors of the Hair Follicle. On the J catheter 85: 480-505
  2. Helwig EB, Hackney VC (1955) Syringocystadenoma papilliferum: Iesion with and without naevus sebaceous and basal cell carcinoma. Arch Dermatol 71: 361-372
  3. Hori K et al (1991) Inverted folliclar keratosis and papillomavirus infection. At J Dermatopathol 13: 145-151
  4. Mehregan AH (1964) Inverted follicular keratosis. Arch Dermatol 89: 117-123
  5. Misago N et al (2002) Sebaceoma and related neoplasms with sebaceous differentiation: a clinicopathologic study of 30 cases. At J Dermatopathol 24: 294-304
  6. Sawaya JL et al (2014) Poroma: a review of eccrine, apocrine, and malignant forms. Int J Dermatol 53:1053-1061.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer