Synonym(s)
malignant tricholemmoma; trichilemmoma malignes; Tricholemmal carcinoma
HistoryThis section has been translated automatically.
Headington, 1976
DefinitionThis section has been translated automatically.
Rare, low malignant carcinoma originating from hair follicles, which histologically mimics tricholemmoma structures, see also Hair follicle tumor.
You might also be interested in
ManifestationThis section has been translated automatically.
Occurring in old age.
LocalizationThis section has been translated automatically.
Located in chronically light-exposed areas (face, ear, neck).
Clinical featuresThis section has been translated automatically.
Uncharacteristic: Relatively rapidly growing, 0.5-2 cm large, erosive-wetting or crusty, exophytic tumor.
HistologyThis section has been translated automatically.
Infiltrating and destructively growing tumor of lobular, usually well-defined structure of differently sized, bright, optically empty cells with chromatin-tight nuclei. Significant cell and nuclear polymorphism, atypical mitoses. Occasional abortive hair formation.
Differential diagnosisThis section has been translated automatically.
- Clinical presentation: Basal cell carcinoma, cornu cutaneum, keratosis actinica.
- Histological: follicular poroma, tricholemmoma, carcinoma of the sebaceous glands.
TherapyThis section has been translated automatically.
Surgical removal in healthy people (safety distance about 3 mm).
Progression/forecastThis section has been translated automatically.
Favourable: In the long term only local growth, very rarely metastasis in the regional lymph nodes.
LiteratureThis section has been translated automatically.
- Headington JT (1976) Tumors of the hair follicle. A review. On J Pathol 85: 481-514
- Misago N et al (2002) Tricholemmal carcinoma in continuity with trichoblastoma within nevus sebaceus. At J Dermatopathol 24: 149-155
- Schell H et al (1986) Tricholemmal carcinoma. Dermatologist 37: 384-38
- Van Zele D et al (2002) Invasive tricholemmal carcinoma of the nose. Dermatology 204: 315-317
Recommended articles
Incoming links (4)
Pilomatrix carcinoma; Sebaceous gland carcinoma; Sebaceous gland carcinoma; Trichilemmoma, malignant;Outgoing links (7)
Actinic keratosis; Basal cell carcinoma (overview); Cornu cutaneum; Hair follicle tumor; Inverted follicular keratosis; Sebaceous gland carcinoma; Trichilemmoma;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer