HistoryThis section has been translated automatically.
Railliet and Henry, 1905
DefinitionThis section has been translated automatically.
Parasitic nematode infection by Ternidens deminutus.
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PathogenThis section has been translated automatically.
- Ternidens deminutus (Nematode, nematode, family: Strongyloidea). Predominantly occurring in the intestine (ileum) of monkeys.
- The adult worms reside in the ileum. The males are 9.5 mm long, the females 14 mm.
- Eggs are excreted with the faeces of the infected host animals. On the ground, rhabditiform larvae initially grow from the eggs, which develop into infectious larvae in the form of filiaries.
- Human infestation occurs when food contaminated with infectious filarial larvae is consumed.
Occurrence/EpidemiologyThis section has been translated automatically.
- Mainly occurring in monkeys (chimpanzees, gorillas, macaques, cercopithecus) in Africa, India, China, Indonesia, Thailand.
- The infestation of humans has been described mainly in indigenous peoples of Africa.
Clinical featuresThis section has been translated automatically.
Mostly abdominal pain, fever, lymphadenopathy, eosinophilia. Intra-abdominal pseudotumours and helminthic abscesses with intestinal and, more rarely, extraintestinal involvement. Non-specific skin reactions are possible, especially maculopapular or urticarial exanthema and prurigo.
DiagnosisThis section has been translated automatically.
Microscopy of faeces: The eggs are similar to those of hookworms, but are larger at 85 x 40 µm.
TherapyThis section has been translated automatically.
In case of suspected intrabdominal pseudotumors or helminthic abscesses surgical intervention is inevitable.
Internal therapyThis section has been translated automatically.
- Albendazole: 400 mg as single dose p.o.
- Alternatively: Mebendazole: 2 times/day 100 mg p.o. for 3 days.
- Alternative: Levamisol and Pyrantel.
LiteratureThis section has been translated automatically.
- Railliet & Henry A (1905) Un nouveau sclerotomien (Triodontophorus deminutus Nov sp.) parasite de 'I' homme. CR Soc Biol 58: 569-571
- Schindler AR, de Gruijter JM, et al (2005) Definition of genetic markers in nuclear ribosomal DNA for a neglected parasite of primates, Ternidens deminutus (Nematoda: Strongylida)--diagnostic and epidemiological implications. Parasitology 131: 539-546
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