DefinitionThis section has been translated automatically.
Vitamin D3 analogue.
Pharmacodynamics (Effect)This section has been translated automatically.
Transformation in the skin by UV light into cholecalciferol, then in the organism into calcitriol: inhibition of DNA synthesis of epidermal keratinocytes.
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IndicationThis section has been translated automatically.
Mild to moderate psoriasis vulgaris of the plaque type.
Notice! Regular determination of plasma calcium level and/or calcium excretion in urine during therapy!
Dosage and method of useThis section has been translated automatically.
Ointment: Apply a thin layer of the ointment once/day to the affected areas of skin (max. 15% of the body surface, max. 10 g ointment/day; max. for 8 weeks). For use up to a maximum of 18 months: 2-3.5 g ointment / day; max. 10% of the body surface.
Standard concentrationThis section has been translated automatically.
Ointment: 0.00004%.
Undesirable effectsThis section has been translated automatically.
Good tolerance, often well controllable skin irritations. Rare: hypercalcemia, calcification of tissues, focal calcification of renal vessels, erythema, exanthema, peeling, pruritus, worsening of psoriasis, folliculitis, skin atrophy, hyperpigmentation.
InteractionsThis section has been translated automatically.
Calcium preparations, salicylic acid, cream bases without active ingredients.
ContraindicationThis section has been translated automatically.
Pregnancy, lactation, children and adolescents < 18 years, large-area application (> 10% KO), psoriasis punctata, psoriasis pustulosa generalisata, diseases of the calcium metabolism, severe liver, kidney or heart diseases, application in intertriginous areas (occlusive effect)
IncompatibilityThis section has been translated automatically.
Externals containing salicylic acid inactivate tacalcitol when used simultaneously and even when used at a later time a few hours before tacalcitol.
PreparationsThis section has been translated automatically.
Curatoderm
PatientinformationThis section has been translated automatically.
Wash your hands after use to avoid transmission to non-diseased skin areas!
Prof. Dr. med. Peter Altmeyer