Streptomycin

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Half-life
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2,8 h

Indication
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Tuberculosis in combination therapies, infections with gram-negative germs, see also gentamicin.

Limited indication
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Restricted kidney function.

Dosage and method of use
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  • Adults: 15 mg/kg bw i.m. or i.v. maximum daily dose 1 g, for patients over 60 years of age max. 0.75 g.
  • Children 30-40 mg/kg bw.

Undesirable effects
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Oto-, neuro-, nephrotoxicity, BB changes, allergic skin reactions (about 10% of patients), contact dermatitis (3-10% of patients).

Contraindication
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Pregnancy, pre-damage of the vestibular or cochlear organ, terminal renal failure.

Preparations
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strepto-fatol, strepto hefa

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Last updated on: 29.10.2020