Sebaceous gland hamartoma, follicular, cystic D23.L

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Folliculosebaceous cystic hamartoma; Sebaceous folliculoma

History
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Plewig, 1980; Kimura, 1991

Definition
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Isolated hamartoma with differentiation of sebaceous glands. The autonomy as an entity is controversial. There may be a variant of a trichofolliculoma.

Localization
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Located on the face and bridge of the nose.

Clinical features
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Circumscribed nodule possibly with bristle-like or fine hairs from a central porus.

Histology
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Cystic, follicular infundibulum, possibly multi-chambered, surrounded by mature sebaceous gland complexes which enter the central, cystic space.

Differential diagnosis
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Therapy
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Due to random histological findings, advance planning is not possible. Excision without a safety margin is sufficient.

Literature
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  1. Aloi F et al (1996) Folliculosebaceous cystic hamartoma with perifollicular mucinosis. At J Dermatopathol 18: 58-62
  2. Bolognia JL, Longley BJ (1998) Genital variant of folliculosebaceous cystic hamartoma. Dermatology 197: 58-260
  3. Donati P et al (1997) Folliculosebaceous cystic hamartoma. J Am Acad Dermatol 36: 02
  4. Kimura T et al (1991) Folliculosebaceous cystic hamartoma. A distinctive malformation of the skin. At J Dermatopathol 13: 213-220
  5. Plewig G (1980) Sebaceous trichofolliculoma. J Cutan Catholic 7: 394-403
  6. Ramdial PK et al (1998) Folliculosebaceous cystic hamartoma. Pathology 30: 212-214
  7. Toyoda M, Morohashi M (1997) Folliculosebaceous cystic hamartoma with a neural component: an immunohistochemical study. J Dermatol 24: 451-457

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Last updated on: 29.10.2020