HistoryThis section has been translated automatically.
Bainier, 1907
General definitionThis section has been translated automatically.
Mildew. Low pathogenetic importance and low contactability in humans. Common in immunocompromised and HIV-infected people. Cultivation: Best from subungual detritus of infected nails. Optimum growth temperature: 24-30 °C.
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Occurrence/EpidemiologyThis section has been translated automatically.
Globally, ubiquitously occurring, e.g. in soil, wood, straw, cereals, fruits (including soya, peanuts, nuts), manure, paper, meat, dairy products (cheese, milk, butter).
ManifestationThis section has been translated automatically.
Mostly occurring in adolescents or young adults in connection with post-traumatic disposition or trophic disorders.
Clinical pictureThis section has been translated automatically.
S.u. Tinea unguium. Infestation of the nail beds of the feet after small traumas, preferably on the big toe. Rarely also infestation of the fingers. Mostly occurring in connection with mycotically changed, yellow-striped nails without previous interdigital mycosis. In chronic cases the mycelium penetrates into the cavities of the nails and spreads like a fern leaf.
MicroscopyThis section has been translated automatically.
- Long septated hyphae, conidiophores (annellophores).
- Conidia: Bulky, uniform, size: 5-10 μm Ø, pearl necklace shape with rough, spiky outer walls ("morning star"), usually standing at right angles to the hyphae.
TherapyThis section has been translated automatically.
For the treatment of onychomycosis caused by Scopulariopsis brevicaulis, itraconazole and terbinafine have shown good efficacy, fluconazole somewhat less.
LiteratureThis section has been translated automatically.
- Gupta AK et al (2001) Efficacy of itraconazole, terbinafine, fluconazole, griseofulvin and ketoconazole in the treatment of Scopulariopsis brevicaulis causing onychomycosis of the toes. Dermatology 202: 235-238
- Filipello Marchisio V et al (2000) Scopulariopsis brevicaulis: a keratinophilic or a keratinolytic fungus? Mycoses 43: 281-292
- Sellier P et al (2000) Recurrent subcutaneous infection due to Scopulariopsis brevicaulis in a liver transplant recipient. Clin Infect Dis 30: 820-823
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Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer
