Ross river virus infectionB33.1

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Epidemic polyarthritis; Ross River Fever; ross river infection; RR

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HistoryThis section has been translated automatically.

Nimmo, 1928; Doherty et al., 1963

DefinitionThis section has been translated automatically.

Infectious disease transmitted by mosquitoes with the Ross-River-Virus (endemo-epidemic arbovirose).

PathogenThis section has been translated automatically.

Ross River Virus; genus Alphavirus, family Togaviridae, belonging to the Semliki Forest complex; belonging to the family Arboviroses.

Occurrence/EpidemiologyThis section has been translated automatically.

  • Endemo-epidemic spread, sporadic cases and small and large epidemics are possible. Occurrence in Southeast Australia, New Caledonia, New Guinea and in the entire Pacific region. Antibodies have also been detected in Solomon Islands, Moluccas and Vietnam.
  • Risk of infection: ca.3%. Morbidity: approx. 1.5%. Major outbreak in 1979/1980 on the Fiji Islands, Samoa, Tonga, Cook Islands.

EtiopathogenesisThis section has been translated automatically.

Transmission by Aedes and Culex mosquitoes. The virus reservoir (in Australia horses and marsupials (kangaroos) is not known for sure. The virus gets through the skin into the synovial cells, multiplies in mononuclear cells, creates toxic exudates that cause the pseudorheumatic complaints and exanthema.

ManifestationThis section has been translated automatically.

Adolescents and adults usually fall ill more frequently and severely than children. Mainly occurring in the months December to June.

Clinical featuresThis section has been translated automatically.

Incubation period: 3-9 days. Febrile myalgia and severe arthralgia (large joints) and joint effusions. Maculopapular exanthema ( viral exanthema) on extremities and trunk. Slow convalescence.

DiagnosisThis section has been translated automatically.

Serum antibodies (ELISA, immunofluorescence).

Differential diagnosisThis section has been translated automatically.

O'nyong-nyong; Chikungunya; dengue fever; other alpha and flavivi roses; rheumatoid arthritis, autoimmune disease.

TherapyThis section has been translated automatically.

Symptomatic, non-steroidal anti-inflammatory drugs.

ProphylaxisThis section has been translated automatically.

Mosquito protection and control.

LiteratureThis section has been translated automatically.

  1. Doherty RL, Whitehead RIF, Gorman BM, O'Gower K (1963) The isolation of a third group A arbovirus in Australia, with preliminary observations on its relationship to epidemic polyarthritis. Aust J Sci 26: 183-184
  2. Nimmo JR (1928) An unusual epidemic. Med J Aust 1: 549-550

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Last updated on: 29.10.2020