O'nyong-nyongA92.1
Synonym(s)
Joint Crusher Virus Infection; ONN virus infection; O'nyong-nyong fever
DefinitionThis section has been translated automatically.
Infectious disease transmitted by mosquitoes with the O'nyong-nyong virus (endemic arbovirosis).
PathogenThis section has been translated automatically.
- O'nyong-nyong virus, genus Alphavirus, family Togaviridae, belongs to the Semliki Forest complex.
- Counted among the arboviroses. Transmission by Anopheles mosquitoes; in the sylvatic cycle (virus was found in sloths), Aedes and Culex mosquitoes.
Occurrence/EpidemiologyThis section has been translated automatically.
- Endemo-epidemic, currently only sporadically occurring.
- Hereditary description in Uganda 1959-1962 during a major epidemic that affected about 2 million people, subsequently spreading to Kenya, Tanzania and Zambia and even to the whole of Equatorial and East Africa.
Clinical featuresThis section has been translated automatically.
Incubation period 4-8 days. Symptoms are chills, fever (not regular) headache and severe symmetrical joint pain of the large joints. On day 4 maculopapular exanthema (spreading from the neck to the trunk) ( viral exanthema), lymphadenopathy. Only slow regeneration and recovery. There is long lasting immunity.
DiagnosisThis section has been translated automatically.
- Serum antibody
- Virus cultivation
- Neutralisation test
- Leukocytopenia
- reactivated lymphocytes.
Differential diagnosisThis section has been translated automatically.
Chikungunya; dengue fever; other alpha and flavivi roses; rheumatoid arthritis, autoimmune diseases.
TherapyThis section has been translated automatically.
Symptomatic with non-steroidal anti-inflammatory drugs.
ProphylaxisThis section has been translated automatically.
Mosquito protection and mosquito control.
Note(s)This section has been translated automatically.
The synonym "joint breaker" virus infection is borrowed from the Bantu (Ganda) language.