Resorcin

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Resorcinol; Resorcinolum

Definition
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1,3-dihydroxybenzene a phenol derivative. The benzene nucleus carries two hydroxy groups in meta position. Resorcinol is isomeric to catechol (1,2-dihydroxybenzene) and hydroquinone (1,4-dihydroxybenzene).

Indication
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Acne vulgaris, psoriasis, seborrhoea.

Recently, a resorcinol preparation (Resorcinol) has been offered in a care series (Eucerin Even Brighter) for the treatment of hyperpigmentation.

Notice! Due to the unfavourable benefit-risk ratio a negative monograph exists for Resorcinol!

Standard concentration
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20% in pastes, 5% in ointments, 2% in solutions, 1% as hair spirit, 20-30% in solutions for chemical peeling.

Remember! When applying the hair spirit on blond or grey hair, red colouring may occur. The substance dyes skin and objects (clothing) red!

Undesirable effects
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Allergic reactions, goiter.

Contraindication
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Infants (poisoning!).

Incompatibility
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Light, air, iron, polyethylene glycols, antipyrine, salicylic acid, salipyrine, pyramidone, cellulose ether, iodine salts, phenazone, menthol, camphor, phenol, acetanilide, urethane.

Note(s)
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The DKG has tested resorcinol in vaseline 1.0% so far. This application form is no longer available as a test substance in Germany. In this respect, a 2% concentration of resorcinol in vaseline is now (as of 2016) recommended.

Literature
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  1. Geier J et al (2016) News on the epicutaneous test series of the German Contact Allergy Group. Dermatology at work and in the environment 64: 70-75

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Last updated on: 29.10.2020