Synonym(s)
Pyrithione zinc; zinc pyrithione; Zinc pyrithione; Zinc Pyrithione
DefinitionThis section has been translated automatically.
Antiekzematosum, antimycotic (see below antimycotics)
IndicationThis section has been translated automatically.
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Dosage and method of useThis section has been translated automatically.
As a monotherapeutic: Cream: once a week, more often in case of severe dandruff, rub into moistened scalp in the evening, rinse thoroughly the next morning.
As a combination therapy with Ciclopirox: shampoo for pityriasis versicolor. Shampoo affected areas, leave to act for 5 minutes and then rinse off. Continue for 1 week. Then repeat the procedure 1 x per week.
Standard concentrationThis section has been translated automatically.
Cream: 1%.
Undesirable effectsThis section has been translated automatically.
Rather rarely. Contact allergy, dyspnoea, discoloration of the hair in blond and grey hair. The environmentally harmful effects of pyrithione zinc have not been conclusively clarified.
ContraindicationThis section has been translated automatically.
Children < 3 years.
PreparationsThis section has been translated automatically.
De-Squaman N Hermal; Kelual DS Shampoo (Ducray)
LiteratureThis section has been translated automatically.
- Housman TS et al (2003) The use of 0.25% zinc pyrithione spray does not enhance the efficacy of clobetasol propionate 0.05% foam in the treatment of psoriasis. J Am Acad Dermatol 49:79-82
- Jo JH et al (2005) Pustular psoriasis and the Kobner phenomenon caused by allergic contact dermatitis from zinc pyrithione-containing shampoo. Contact dermatitis 52:142-144
- Lamore SD et al (2011) Zinc pyrithione impairs zinc homeostasis and upregulates stress response gene expression in reconstructed human epidermis. Biometals 24:875-890
Prof. Dr. med. Peter Altmeyer