Pyrantel

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

Broad-spectrum anthelmintic.

Half-lifeThis section has been translated automatically.

26 h

Pharmacodynamics (Effect)This section has been translated automatically.

Spastic paralysis due to depolarisation (neuromuscular blockade) and thus excretion of the worms.

IndicationThis section has been translated automatically.

Infections caused by Ancylostoma duodenale, Askaridiasis, Enterobius vermicularis, Necator americanus, Trichostrongylus spp.

Limited indicationThis section has been translated automatically.

pregnancy, liver dysfunction.

Dosage and method of useThis section has been translated automatically.

  • Oxyuriasis/Ascariasis:
    • Pat. < 12 kg KG: 125 mg as ED.
    • 12-22 kg bw: 250 mg.
    • 22-40 kg bw: 500 mg.
    • 41-75 kg bw: 750 mg.
    • > 75 kg KG: 1 g.
  • Hookworms: above scheme over 3 days.

Undesirable effectsThis section has been translated automatically.

Gastrointestinal disorders, increase in transaminases, headaches, dizziness, fatigue, insomnia, allergic skin reactions, fever.

InteractionsThis section has been translated automatically.

Piperazine and pyrazinobutazone lead to a mutual reduction in effectiveness, the theophylline level is increased.

ContraindicationThis section has been translated automatically.

Children < 6 months, breastfeeding (take a break!), 1st trimester pregnancy.

PreparationsThis section has been translated automatically.

Helmex

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer