Synonym(s)
HistoryThis section has been translated automatically.
DefinitionThis section has been translated automatically.
Rare, non-infectious, inflammatory disease of the oral mucosa, in a few cases also of the genito anal region. There are often associations with inflammatory bowel diseases. Some authors regard it as a minimal variant of pemphigus vegetans, type Hallopeau. Other authors evaluate the disease as a variant of Pyoderma gangraenosum.
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EtiopathogenesisThis section has been translated automatically.
ManifestationThis section has been translated automatically.
LocalizationThis section has been translated automatically.
Clinical featuresThis section has been translated automatically.
Start with miliary pustules, confluence and ulceration on erythematous ground. Frequently the pustules are arranged in lines and serpentines, later a patch-like picture of the entire oral cavity with a layer of mucous membranes. Sometimes mild pain, sometimes severe pain.
Very often the clinical picture is correlated with chronic inflammatory bowel diseases such as Crohn's disease or ulcerative colitis.
HistologyThis section has been translated automatically.
Direct ImmunofluorescenceThis section has been translated automatically.
Indirect immunofluorescenceThis section has been translated automatically.
Differential diagnosisThis section has been translated automatically.
Pemphigus vegetans, type Hallopeau: histologic and immunohistologic clarification
Amicrobial intertriginous pustulosis: intertriginous localization preferentially in women, usually in the context of an autoimmune disease.
TherapyThis section has been translated automatically.
External therapyThis section has been translated automatically.
Astringent stomatological products such as tormentillae astringents, chlorhexidine solution or dexpanthenol solution R255 R045 R066. In case of very painful erosions, solutions with anaesthetic additives such as Dolo-Dobendan solution, Acoin solution, periodontal ointment or Dynexan gel are suitable. Alternatively Ciclosporin A-adhesive paste(Ciclosporin A-adhesive paste 2.5%) can be tried.
Internal therapyThis section has been translated automatically.
LiteratureThis section has been translated automatically.
- Ballo FS et al (1989) Pyostomatitis vegetans. J Am Acad Dermatol 21: 381-387
- Bens G et al. (2003) Successfull treatment with infiliximab and methotrexate of pyostomatitis vegetans associated with Crohn`s disease. Br J Dermatol 149: 181-184
- Hallopeau H (1889) Sur une nouvelle forme de dermatite pustuleuse chronique en foyers à progression excentrique. In: Congrès International de Dermatologie et de Syphiligraphie tenu à Paris (Ie session). Masson, Paris, pp. 344-362
- Hallopeau H (1898) "Pyodermite végétante", its relations to dermatitis herpetiformis and pemphigus vegetans. Arch Dermatol Syphil 43: 289-306
- Hallopeau H (1898) Second communication on "Pyodermite végétante" (suppurative form of Neumann's disease). Arch Dermatol Syphil 45: 323-328
- Lobkowicz F et al (1991) Pyostomatitis vegetans. Dermatologist 42: 92-95
- Nusbaum KB et al (2020) Pyostomatitis vegetans with extensive tongue involvement. Int J Dermatol 59:e263-e265.
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Incoming links (9)
Amicrobial intertriginous pustulose; Chlorhexidine mouth rinse solution 0.1 or 0.2% (nrf 7.2.); Ciclosporin a adhesive paste 2,5%.; Dexpanthenol solution 5% (nrf 7.3.); Intestinal diseases, skin changes; Pemphigus vegetans type hallopeau; Pyoderma gangraenosum; Pyo-(rhino-blepharo-)stomatitis vegetans; Tormentil myrrh astringent (nrf 7.1.);Outgoing links (20)
Acantholysis; Acanthosis; Amicrobial intertriginous pustulose; Chlorhexidine; Chlorhexidine mouth rinse solution 0.1 or 0.2% (nrf 7.2.); Ciclosporin a; Ciclosporin a adhesive paste 2,5%.; Crohn disease, skin alterations; Dexpanthenol; Dexpanthenol solution 5% (nrf 7.3.); ... Show allDisclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer