Synonym(s)
Lidocaine hydrochloride
DefinitionThis section has been translated automatically.
Amide-type local anesthetic.
Half-lifeThis section has been translated automatically.
1,8-3,5 h (metabolites).
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IndicationThis section has been translated automatically.
Topical: Infiltration, surface and conduction anaesthesia and pruritus.
Systemic: antiarrhythmic agent for ventricular arrhythmias.
Standard concentrationThis section has been translated automatically.
- 0,5-2 % for infiltration and block anaesthesia (max. 4 mg/kg bw),
- 2-5% as ointment, solution or gel for surface anaesthesia.
Remember! Topical application is considered controversial because of the danger of developing contact allergies!
Undesirable effectsThis section has been translated automatically.
In case of (accidental) i.v. injection: euphoria, drowsiness, muscle twitches; in high doses: cramps, dyspnoea, respiratory paralysis.
In case of topical application: late type allergy, otherwise intolerance phenomena.
InteractionsThis section has been translated automatically.
Synergism with other local anesthetics, increase in neuromuscular block of muscle relaxants, with simultaneous use of Cotrimoxazole: methemoglobinemia.
ContraindicationThis section has been translated automatically.
Thigh or AV block, liver damage.
PreparationsThis section has been translated automatically.
Lidocaine, LidoPosterols, Xylocaine; periodontal mouth ointment (combination of lidocaine, chamomile flowers and sage fluid extracts)
Prof. Dr. med. Peter Altmeyer
